The San Francisco 49ers are facing the Las Vegas Raiders at Allegiant Stadium in a preseason matchup. While most starters sat out last weekend's opener, several key players took the field in this weekend's game.
Below are the latest in-game injury updates for the 49ers. This article will be updated in real time as new information becomes available.
Corey Kiner went down after a 19-yard run in the second quarter. He was carted off the field. The 49ers announced that Kiner has been ruled out with an ankle injury.
The 49ers announced in the first quarter that Dominick Puni has been ruled out due to a knee injury. The injury seems to have occurred on the field-goal attempt at the end of the opening drive.
Puni got rolled upon a FG attempt https://t.co/QR2GtIxoPr pic.twitter.com/ePpTymcoy7— ???????????????????????????????????????????? (@TheSFNiners) August 16, 2025
Seeing #49ers Dominic Puni sitting on the bench is a GREAT SIGN pic.twitter.com/j2HYYhQz4H— Jennifer Lee Chan - also bluesky @jenniferleechan (@jenniferleechan) August 16, 2025
Also - no wraps or support devices on #49ers OL Dominic Puni's knee pic.twitter.com/6BOw7quoQK— Jennifer Lee Chan - also bluesky @jenniferleechan (@jenniferleechan) August 16, 2025
The 49ers also reported that Patrick Taylor is questionable to return after sustaining a shoulder injury.
Update: The 49ers eventually ruled out Taylor.
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