Eagles dominating sportsbooks with two of the widest spreads in 2025 NFL campaign

Out of the gates from the 2025 NFL schedule release, the Philadelphia Eagles arguably have one of the toughest schedules in the league, but have some favorable ones also.

The Eagles' Week 1 opponents were first announced as they would face their NFC East rival, the Dallas Cowboys. DraftKings Sportsbook had Philadelphia is favored to win that game by seven points in the early game odds.

It's no surprise, as the Eagles earned a second Super Bowl title last year and Dallas finished with a 7-10 record after losing to Philadelphia twice in the worst way. This isn't the only game on the calendar that will make it easy bets on the Eagles to win.

Which games are the easiest ones to place a bet on the Eagles?

DraftKings Sportbook shared its list of the largest opening spreads of the 2025 NFL season. The Eagles had two games tied for third alongside the Detroit Lions-Cleveland Browns matchup, which also had a -10.5 point spread.

Tied-Third Week 9 vs. New York Giants (-10.5)

"Also tied for the third-largest spread across this 2025 NFL season, the defending Super Bowl Champion Philadelphia Eagles will host the New York Giants as 10.5-point favorites on DraftKings Sportsbook. This NFC East battle will hold some increased buzz following the quarterback upgrades made in New York, but Philadelphia kept its championship core intact and will hold the same aspirations this season.

The Philadelphia Eagles will enter the season as favorites to win the Super Bowl for the second straight season at +650 odds on DraftKings Sportsbook. They also hold +310 odds of winning the NFC and are -140 favorites to win the NFC East."

To say the Eagles have owned the Giants in recent years would be an understatement. Looking back in 2024, Philadelphia won both matchups with their second game just as impressive as their 28-3 victory earlier in the season as the backups got the Eagles a 20-13 win over New York to close out the season.

The Eagles own the overall series against the Giants at 95-88-2. In 2016, Philadelphia won 19 out of 23 matchups against New York.

It's a rebuild year for the Giants with a new quarterback, head coach Brian Daboll, and general manager Joe Schoen is on the hot seat. Two losses against the Eagles in three weeks could cause some changes made in the Big Apple.

Tied -Third Week 15 vs. Las Vegas Raiders (-10.5)

"For the second time on this list, the Philadelphia Eagles will host the Las Vegas Raiders as 10.5-point favorites. These two teams last met in the 2021 season, where the Raiders won 33-22, but Philadelphia holds a 7-6 all-time record in these matchups. Las Vegas turned a page on last year’s 4-13 season by firing Antonio Pierce and making some notable changes. Pete Carroll has stepped in as head coach and has been reunited with Geno Smith as his quarterback, but this will be quite the measuring stick matchup."

These two teams have not played each other as often, but Eagles fans will remember the 27-10 blowout loss to the Raiders in Super Bowl 15 in 1981. This loss still haunts Philadelphia sports as it was the first heartbreaking Super Bowl loss.

The last eight matchups against both teams are an even 4-4 record. Philadelphia has been the better team, with two of the previous three matchups going in their favor. Las Vegas did capture a 33-22 win the last time these two teams played in 2021.

It's also a rebuild year for the Raiders as Pete Carroll takes over Las Vegas as head coach, and quarterback Geno Smith is one of many new faces in the franchise. Carroll is a great coach, but the Eagles should be able to find an easy time winning with their talent in all three phases of the game.