Even Vegas believes the Eagles are going to crush the Cowboys in Week 1

Anyone ready to start placing their bets on NFL games will be relieved to know that the NFL made it easy for fans to bet on the Philadelphia Eagles in Week 1.

On Monday, the first official confirmed game to be played in the 2025 NFL regular season was announced to be the Dallas Cowboys traveling to Philadelphia to take on the defending Super Bowl champion Eagles. This will mark the first time the two teams have faced off against each other in Week 1 since 2000.

What will make this bet easier than other season-opening games in the past is that recent history shows the Eagles have dominated the Cowboys. Just last year, Philadelphia outscored Dallas 75-13 as the Eagles won both matchups.

Vegas isn't shying away from the fact that bettors should place their money on the Eagles to start the season.

Early betting odds for Eagles-Cowboys Week 1 clash favor Philadelphia

DraftKings Sportsbook released its opening betting lines for the Eagles-Cowboys game, which are all in favor of the Eagles. Here is what they have in the game with the odds:

• Spread: Eagles -7, Cowboys +7
• Total: O/U 46.5, -110
• Moneyline: Eagles -310, Cowboys +250

Philadelphia is favored to win the game by seven points, which is extremely high for a season-opening game. Besides the dominance of the Eagles in their two matchups against the Cowboys last year, contributing factors include Philadelphia having come off winning the Super Bowl and Dallas missing the postseason last year with a 7-10 record.

The next line of DraftKings betting odds are for individual players, when they will score, and how often they will score. Philadelphia owns the top four spots, with Cowboys wide receiver CeeDee Lamb being the only Dallas player in the top five. Here's a look at who has the best chances to score in the game:

• Saquon Barkley: First TD Scorer+360, Anytime TD -205, 2+ TDs +260
• Jalen Hurts: First TD Scorer +55-, Anytime TD -115, 2+ TDs +475
• A.J. Brown: First TD Scorer +800, Anytime TD +125, 2+TDs +950
• DeVonta Smith: First TD Scorer +950, Anytime TD +160, 2+ TDs +1300
• CeeDee Lamb: First TD Scorer +1000, Anytime TD +140, 2+TDs +1000

Betting lines change all the time before the games begin, so there is a chance that it could move up or down in any category. It feels as though the Eagles will still be the favorites in the game, regardless of how much the betting lines could move.