NFL Week 10 Predictions: 49ers Lead Picks Over Buccaneers, Chargers Heavy Fan Favorites

The Tampa Bay Buccaneers will host the San Francisco 49ers at Raymond James Stadium in Tampa, Florida, on Sunday, November 10, at 10:00 a.m. PT. The 49ers are currently favored by 6.5 points.

Each week, 49ers Webzone staff members participate in the NFL Pick 'em contest,predicting the winners of every NFL game. For Week 10, five out of six participating staff members have picked the 49ers to beat the Buccaneers.

As of this post, 92 percent of fans in our NFL Pick 'em contest are also predicting a 49ers victory.

Most One-Sided Matchup: Titans at Chargers

Of all the Week 10 predictions, Sunday's game between the Tennessee Titans and Los Angeles Chargers stands out as the most one-sided, with 98 percent of fans expecting the Chargers to win.

Most Competitive Matchup: Jets at Cardinals

Sunday's game between the New York Jets and Arizona Cardinals is the most evenly split, with 57 percent of fans predicting a Cardinals victory.

Week 10 NFL Matchups

Below is a breakdown of all 13 matchups for the upcoming slate of NFL games.