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Patriots at 49ers, Week 4 Predictions: Confidence in Niners Runs High

Originally posted on 49ers Webzone | Last updated Sep 28, 2024 9:27 PM ET

The San Francisco 49ers will host the New England Patriots at Levi's Stadium in Santa Clara, California, on Sunday, September 29, at 1:05 p.m. PT. Each week, the 49ers Webzone staff participates in the annual NFL Pick 'em contest, where writers and forum moderators predict the winner of each game.

This week, five of the six participating staff members have selected the 49ers to beat the Patriots. San Francisco is currently a 10.5-point favorite.

As for the fans participating in our NFL Pick 'em contest, 97 percent have predicted a 49ers victory, as of this post.

Among the Week 4 game predictions, the 49ers-Patriots matchup stands out as the most one-sided.

Meanwhile, the closest matchup in terms of predictions is Sunday's game between the Cleveland Browns and the Las Vegas Raiders, with 53 percent favoring the Raiders.

Below is a breakdown of all 15 matchups for the upcoming slate of NFL games.

Picks	Away	Home	Picks
55%	Saints	Falcons	45%
61%	Rams	Bears	39%
56%	Vikings	Packers	44%
73%	Steelers	Colts	27%
6%	Broncos	Jets	94%
60%	Eagles	Buccaneers	40%
84%	Bengals	Panthers	16%
4%	Jaguars	Texans	96%
31%	Commanders	Cardinals	69%
3%	Patriots	49ers	97%
47%	Browns	Raiders	53%
82%	Chiefs	Chargers	18%
45%	Bills	Ravens	55%
46%	Titans	Dolphins	54%
12%	Seahawks	Lions	88%