TreVeyon headlines three running backs that could be available for the Buffalo Bills in the second round of the 2025 NFL Draft

With the reports that James Cook and the Buffalo Bills aren't currently heading in the right direction, the next logical conversation turns to how Brandon Beane is going to handle the situation with only two weeks until the 2025 NFL Draft. Will Cook be on the trade block? Will Beane draft a successor in a loaded running back class?

It's worth taking a look at some running backs that could be available, especially in the second round where Beane currently holds two picks. Let's take a look at three of the top options that could be available.

TreVeyon Henderson, Ohio State

While Ashton Jeanty had a monster of a season and is well deserving of being the first running back selected, with Omarion Hampton often sliding in as the second option, Ohio State's TreVeyon Henderson has dominating elite upside as a true three-down, workhorse back capable of doing everything.

We know how much the Bills value blocking. Henderson is a stone wall in pass protection. The 5-foot-10, 202 lbs running back turned in very solid athletic testing at the NFL Scouting Combine after producing 3,761 rushing yards and 42 rushing touchdowns over his college career. He's a special running back that's dominant after contact (4.43 yards after contact per attempt last season) that's an equally potent threat in the passing attack. Quite frankly, he's a better running back prospect coming out college than James Cook was, by a lot.