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Carmelo Anthony, USA
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Anthony averaged 16.3 points per game in 2012 for Team USA, and will be a key part of the offense again this year with LeBron James and Stephen Curry notably missing from the team.
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Simone Biles, USA
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Biles has a chance to be the breakout star of Rio, with a realistic shot at multiple gold medals in women's gymnastics. She's most notably favored to win the beam, floor exercise, and all-around competitions.
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Usain Bolt, Jamaica
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Bolt holds the world record for the 100 and 200 meter sprints, and is looking to medal again despite turning 30 by the end of the games.
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Novak Djokovic, Serbia
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The No. 1 men's tennis player in the world is hoping to win an Olympic medal for the first time, and hopefully bring a gold medal home to Serbia.
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Kevin Durant, USA
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Durant has been the talk of the NBA offseason after leaving Oklahoma City to sign with the Warriors. Now he's considered the leader of Team USA basketball after leading the team in scoring during 2012.
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Cate Campbell, Australia
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Campbell is competing in his third Olympics. She holds the world record in the women's 100 meter freestyle, and has a chance to find gold in both that event and the 50 meter freestyle.
7 of 25
Lisa Carrington, New Zealand
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Carrington is a frontrunner to win both the K1 200 meter and K-1 500 meter canoe sprint after capturing gold in the K-1 200 meter at the London Games in 2012.
8 of 25
Ashton Eaton, USA
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Eaton is hoping to accomplish repeat Olympic decathlon wins after earning the gold medal at the London Games. He's favored after winning gold in the 2015 World Championships.
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Mo Farah, Great Britain
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Farah is perhaps Great Britain's best long distance runner ever. At age 33, he's hoping to add to his two gold medals from London with repeat wins in the 10,000 meter and 5,000 meter runs.
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Allyson Felix, USA
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Felix took home three gold medals in London after medaling three times over the previous two Olympics. She has a chance in the 400 meter and 200 meter, as well as the 4x100 and 4x400 meter relays.
11 of 25
Shelly-Ann Fraser-Pryce, Jamaica
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Fraser-Pryce is Jamaica's female track and field star, alongside male star Usain Bolt. She has four Olympic medals to her name from the last two Olympics, and has an excellent chance to medal again in the 100 meter and 200 meter sprints.
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Justin Gatlin, USA
Shelly-Ann Fraser-Pryce
Gatlin stands neck-and-neck with Usain Bolt in the 100 meter and 200 meter sprints. He won bronze in the 100 meter in London, and is most recently coming off silver medal wins in both events at the 2015 World Championships.
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Nikola Jokic, Serbia
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Jokic averaged 10.0 points and 7.0 rebounds in his rookie season for the Nuggets, and the 21-year-old center will now be leading the Serbian men's basketball team in Rio. The Serbians have a good chance to medal in the tournament.
14 of 25
Mitch Larkin, Australia
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Larkin won three medals, including two gold medals, at the 2015 World Championships. The Aussie will compete in the 100 meter and 200 meter backstroke events at Rio, as well as the 4x100 meter medley relay.
15 of 25
Katie Ledecky, USA
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Ledecky won gold in the 800 meter freestyle in London at age 15. She has a chance to do much more after earning five gold medals at the 2015 World Championships. She's heavily favored to win the 400 meter and 800 meter freestyle events.
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Carli Lloyd, USA
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Lloyd helped lead Team USA to victory in the 2015 FIFA Women's World Cup. She will play a key role as the team tries to win the gold medal in Rio, participating in her third Olympics.
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Alex Morgan, USA
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Morgan is participating in her second Olympics for Team USA women's soccer. She hopes to win her second gold medal as a key forward for the squad.
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There are high expectations for Brazilian men's soccer at the Rio Olympics as the hosts, and Neymar is the team's clear star. He sat out Copa America based on an agreement between his club team and the Brazilian Football Confederation.
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Federica Pellegrini, Italy
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Pellegrini is hoping to rebound after failing to medal in the 200 meter freestyle at the London Games. She won silver in the event in 2004 and gold in 2008 for Italy.
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Michael Phelps, USA
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In what will more than likely be Phelps' last Olympics, he's set to add onto his 22 career Olympic medals, including 18 gold medals. He won four golds in London, and could match that count in Rio.
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Bruno Rezende, Brazil
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Brazilian men's volleyball is favored in Rio, and Rezende is their captain. The Brazilians won silver in Athens and London.
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Kohei Uchimura, Japan
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Uchimura has five Olympic medals accumulated over the last two Olympics, but he only has one gold to his name. The Japanese gymnast is favored for repeat gold in the all-around, and could also win the horizontal bar.
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Oleg Vernyayev, Ukraine
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Vernyayev has become a star gymnast for Ukraine, medaling in the parallel bars at the last two World Championships. He's favored to win gold in the event in Rio, and is also a candidate to win the all-around.
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Kristina Vogel, Germany
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Vogel won gold in the cycling team sprint at the London Games, and could be set to medal in three events this time around, adding individual sprint and keirin.
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Serena Williams, USA
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Williams is coming off a win at Wimbledon, and hopes to win her fifth Olympic gold medal in Rio. She's won doubles three times, and claimed gold in singles tennis in 2012.