NFL betting: A look ahead to some intriguing Week 3 matchups 

Who should you back in the Eagles-Saints matchup?

Who would've thunk it -- the Saints are 2-0 while the Eagles are 1-1 after a 22-21 upset loss to the Atlanta Falcons. As such, the betting line has shifted from favoring Philadelphia at 3.0 points to favoring New Orleans at 2.5.

Honestly, betting the spread on this one is tricky since the Eagles haven't lost at the Superdome since 2019. Betting the over/under, however, looks pretty darn good.

The Saints have eclipsed the 40-point marker in back-to-back games. (Congrats to all of you with Alvin Kamara on your fantasy roster.) The over/under of 49.5 points is priced at -110 each way at DraftKings. It may not be plus money, but an offensive matchup like this one promises to run up the scoreboard.

Should you back Goff to bounce back against the Cardinals?

In another interesting matchup, Kyler Murray and the Cardinals are coming off of a colossal 41-10 upset against the Los Angeles Rams. They host a Lions team that was stunned by the Tampa Bay Buccaneers 20-16 in a game where Goff threw two interceptions and no touchdowns.

Still, the Lions are 3-point favorites at DK to win on Sunday. How is this possible? Because Goff hasn't lost to Arizona since his rookie season in 2016.  

He has won eight consecutive games since then. In his lone start against them with Detroit, he completed 21 passes for 216 yards with three touchdowns and no interceptions. (h/t Statmuse). DK has him listed at +800 odds to score a TD at anytime on Sunday, and he has a great foundation to have a bounce-back game and find the endzone.

Should you back anyone in the Falcons-Chiefs Sunday night matchup?

Honestly, you may want to shy away this game altogether. And not just because Isiah Pacheco was placed on IR this week.

Yes, the defending Super Bowl champs are 2-0 on the season. They also failed to cover the spread in a close win against the Cincinnati Bengals in Week 2. The defense has had to pick up for the offense not quite finding its groove yet, which includes star tight end Kelce recording just four receptions in two games. 

Plus, Kansas City was 1-5 ATS in regular-season primetime games last season, which isn't good as they gear up for the Sunday Night Football stage.

The Falcons have an underrated defense and a Bijan Robinson-led run game that has more jump to start this season. Then again, Atlanta hasn't played a SNF game since 2019 and have lost their last two meetings against the Chiefs.

The Chiefs haven't reached their full potential yet and the Falcons are unpredictable. Whether it's spread betting or knockout picks, this is a risky game to wager on.