Saints vs. Chiefs picks, odds, spread: 'Monday Night Football' predictions

• Saints vs. Chiefs spread: Chiefs -5.5, -110 | Saints +5.5, -110
• Saints vs. Chiefs over/under: o43, -111 | u43, -110
• Saints vs. Chiefs moneyline: Chiefs -250 | Saints +202

Spread

As the Chiefs aim to defend their unblemished record, they are favored by 5.5 points with odds of -110.

Over/Under

The over/under is set at 43 points.

Moneyline

The moneyline is set at Chiefs -250, Saints +202.

Player Prop

PRO Projections peg Saints QB Derek Carr‘s passing yards at 215 – slightly higher than the line of 208.5.

It’s only a +1.6% edge. PRO Projections recommend a 3.5% or better when tailing, so this one doesn’t exactly meet the criteria.

Saints vs. Chiefs Prediction

Split opinions surround the "Monday Night Football" spread. Two of our top NFL experts, representing a 100% consensus, are backing the Saints to cover. Conversely, sharp action has emerged on the Chiefs, indicating contrasting perspectives among seasoned bettors.

Total

The sharpest Chiefs vs. Saints pick in PRO Report at the time of writing is the under. Sharp action and both of our top experts advocate for a low-scoring game, coinciding with a market move down from 43.5.

Moreover, big money influence supports this stance, with 51% of the money on the under despite comprising just 19% of total bets.

Odds to Win

There are no PRO signals active in this market at the time of writing.

Our PRO Pick

Leveraging PRO insights and analyzing expert consensus, it’s evident the best betting choice for this game aligns with the under. The combination of expert backing, sharp money and prime-time trends all point to the under.

Chiefs vs. Saints Betting Trends

Here are some betting trends courtesy of our researcher, Evan Abrams:

• Carr is 24-35-2 ATS on the road since 2017, the least profitable road QB ATS in that span (135 of 135 QBs). He’s 26-26-1 ATS at home in that span.
• In Mahomes’ career, he is 25-8-1 ATS in games where he closes -3 or shorter or is an underdog. When he is above -3, he is 38-43-3 ATS career.

Our PRO signals flag far more great picks than our staff could author each day — that’s where Action AI comes in. Using generative AI, signals that hit a high grade threshold are written up into articles that are then vetted and edited by a human to help us get you all the sharp action. Read more about how it works here.