The first major upset of the 2025 NCAA Tournament is in the books.
The 12-seed in the Midwest Regional, McNeese State, knocked out the fifth-seeded Clemson Tigers 69-67 in what became a tight finish in the final minute of regulation.
The Cowboys led by as many as 24 points in the second half before the Tigers stormed back to come within two. However, it came seconds too late, and Clemson's final bucket went through the hoop as time expired.
UPSET ALERT
— NCAA March Madness (@MarchMadnessMBB) March 20, 2025
(12) McNeese completes the upset against (5) Clemson #MarchMadness @McNeeseMBB pic.twitter.com/Lga7nfI35n
The historic performance was McNeese's first-ever victory at an NCAA Tournament.
McNeese head coach Will Wade graduated from Clemson in 2005, serving as a student manager, graduate assistant and director of basketball operations until 2007.
Eliminating his alma mater wasn't on his mind, though.
"We've made school history," he told CBS Sports' Evan Washburn post-game. "It's incredible, this changes our university."
The 42-year-old successfully kept his professional prospects from becoming a distraction for his players.
Wade reportedly agreed to become NC State's next head coach on Wednesday, but that new role will have to wait after Thursday's unexpected result.
Not many fans believed in the Southland Conference champions, either. According to ESPN, only 18.3 percent of submitted brackets picked the Cowboys to advance, and only 1.4M perfect predictions remain (5.7 percent).
That's the definition of a "bracket buster." The 2025 tournament may have identified its first Cinderella candidate.
McNeese will face the No. 4 seed Purdue Boilermakers on Saturday in the Round of 32.
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