The Big Ten and Big 12 each had huge Associated Press top 25 showdowns end in blowouts, while Clemson and Florida extended their misery with losses.
These are Week 4's winners and losers.
So much for being a one-year wonder. No. 19 Indiana (4-0, 1-0 in Big Ten) embarrassed No. 9 Illinois Fighting Illini (3-1, 0-1 in Big Ten), 63-10, jumping out to a stunning 35-7 halftime lead. Quarterback Fernando Mendoza entered the Heisman race with an unreal performance, going 21-of-23 for 267 yards and five touchdowns, and the Hoosiers defense allowed 161 yards, including two rushing. While other inaugural 12-team College Football Playoff participants, Boise State, Clemson and SMU have sustained some debilitating losses, Indiana has avoided a 2025 hangover. Instead, it might be better.
These Gators are more cooked than the kind you might find at a Cajun restaurant. Florida (1-3) dropped its third consecutive game in Saturday's 26-7 loss to No. 4 Miami Hurricanes (4-0) and gained just 32 yards of offense in the first two quarters. Quarterback D.J. Lagway, the top quarterback recruit in the 2024 high-school class, continues to regress following last week's five-interception game against the LSU Tigers, going 12-of-23 for 61 yards versus the Hurricanes. Head coach Billy Napier received a vote of confidence from the athletic department less than a year ago, but with the program taking a massive step back, its tune has likely changed.
After an offseason rebrand, The American is looking to also be known as the best college football non-power conference. It's off to a good start.
One day after the Tulsa Golden Hurricane defeated the Oklahoma State Cowboys, 19-12, the Memphis Tigers gave The American its sixth power conference win this season in a 32-31 thriller over the Arkansas Razorbacks (2-2, 0-1 in SEC). The South Florida Bulls (3-1) also defeated then-No. 25 Boise State Broncos (1-1) in Week 1, while the North Texas Mean Green notched a dominant 59-10 win over Washington State (2-1) last Saturday. With several crown jewels during the non-conference portion of the schedule, The American has positioned itself nicely to earn an auto-bid in this year's College Football Playoff.
"If they're tired of winning, they can send me on my way," a defiant Clemson head coach, Dabo Swinney, told reporters earlier this week. Who knew that may have actually been a plea?
The Tigers dropped to 1-3 for the first time since 2004 on Saturday following a listless performance in a 34-21 home loss to the Syracuse Orange (3-1, 1-0 in ACC). "This is a very, very low day," Swinney said afterward, per Sports Illustrated. With more than half of the regular season remaining, Clemson can still plunge lower.
In the first high-profile Big 12 conference game of the season, No. 17 Texas Tech (4-0, 1-0 in Big 12) defeated No. 16 Utah Utes (3-1, 0-1 in Big 12), 34-10, with starting quarterback Behren Morton leaving the game after taking a hit to the helmet early in the third quarter. Backup Will Hammond was marvelous in the tough road environment, going 13-of-16 for 169 yards and two touchdowns, and the Red Raiders outscored the Utes 24-7 in the fourth quarter.
The defense bottled Utah, limiting the Utes offense to 263 total yards and quarterback Devon Dampier to 4.3 yards per pass attempt. The unit had four tackles for loss, two interceptions and two forced fumbles.
Texas Tech left no doubt that it is the far superior team, also staking a claim as the best of the Big 12 in the process. If it can thoroughly dominate a ranked opponent with a backup quarterback playing most of the second half, Texas Tech should be able to handle most other hurdles it comes across.
The Nebraska Cornhuskers (3-1, 0-1 in Big Ten) and No. 22 Auburn Tigers (3-1, 0-1 in SEC) could have made major statements with wins, but both instead showed they have significant shortcomings along the offensive line.
Nebraska fell, 30-27, to No. 21 Michigan Wolverines (3-1, 1-0 in Big Ten), its 28th consecutive loss against an AP-ranked opponent, and quarterback Dylan Raiola was sacked seven times. Michigan was able to get to the sophomore quarterback with four-man pressures, and Nebraska finished with more third-down sacks allowed (four) than conversions (two).
Dylan Raiola limps off after a @UMichFootball sack pic.twitter.com/2BAv3fSCz6
— CBS Sports College Football (@CBSSportsCFB) September 20, 2025
"They just can't hold up against the Michigan pressure."@UMichFootball with SEVEN sacks so far on the day. pic.twitter.com/1lHGa7CcfA
— CBS Sports (@CBSSports) September 20, 2025
"I couldn't believe [Nebraska] kept leaving them on islands," CBS Sports college football studio analyst Rick Neuheisel commented at halftime.
"I couldn't believe they kept leaving (the O-tackles) on islands."@CoachNeuheisel on Michigan's seven sacks against the Huskers pic.twitter.com/2kG3qZV0vQ
— CBS Sports College Football (@CBSSportsCFB) September 20, 2025
Auburn's line fared even worse against No. 11 Oklahoma (4-0, 1-0 in SEC), allowing an astonishing 10 sacks in a 24-17 loss, including on back-to-back plays with under two minutes remaining, the latter resulting in a safety.
THE CLOSER ❌ pic.twitter.com/52CEKm6NF3
— Oklahoma Football (@OU_Football) September 20, 2025
Unless the two units improve, head coaches Matt Rhule (Nebraska) and Hugh Freeze (Auburn), both hired during the 2023 offseason cycle, won't see the Year 3 gains necessary for their respective programs to feel good about the direction they're headed.
The iron skillet is headed to TCU (3-0). The Horned Frogs defeated the 2024 ACC runner-up and CFP participant SMU Mustangs (2-2), 35-24, in the spirited rivalry game, and Hoover and McAlister starred.
The fourth-year junior was 22-of-40 for 379 yards, five touchdowns and an interception in the win. McAlister finished with eight receptions for 254 yards, the second-most in program history, and three touchdowns. Three years removed from a run to the CFP national championship game, TCU might be back.
Anyone paying attention to the work Dilfer's done at UAB since 2023 wasn't surprised that his team was severely outclassed against No. 15 Tennessee Volunteers (3-1, 0-1 in SEC), 56-24. Yet the Blazers still failed to reach the lowest of expectations, with Dilfer casually on his cell phone moments before kick off. During the game, redshirt senior safety Sirad Bryant displayed a shocking lack of sportsmanship when he went out of his way to step on Tennessee kicker Max Gilbert's foot after one of his eight extra points.
Trent Dilfer had to get that last text in before today's game against Tennessee pic.twitter.com/dEkyJVimFp
— Awful Announcing (@awfulannouncing) September 20, 2025
??? uhh ejection??????? pic.twitter.com/tys9NModJ5
— gmannVOLS (@gmannVOLS) September 20, 2025
The Dilfer era could end on Saturday, and it wouldn't be soon enough.
Louisville offered an important reminder in Week 4: It pays to be nice. The Cardinals rolled out the red yarn for the Bowling Green Falcons and their prrr-fect adopted feline mascot, Pudge, giving the internet sensation his own locker and a typed letter welcoming him to the stadium.
Big thank you to @GoCards for the Pudge hospitality
— BGSU Football (@BG_Football) September 20, 2025
WE LOVE IT!!!! pic.twitter.com/c9C1S0j216
Karma (and quarterback Miller Moss) rewarded Louisville with a resounding 40-17 win.
During the early afternoon window, the North Texas Mean Green (4-0, 1-0 in American), Miami (Ohio) Redhawks (0-3), and Arkansas each had costly fumbles on designed run plays in key situations, proving that even the most conservative play calls can result in calamity.
North Texas sophomore running back Makenzie McGill II fumbled up three, 38-35, with under three minutes remaining in the fourth against the Army Black Knights (1-2, 0-1 in American), who sent the game to overtime with a field goal.
ARMY!!! The Black Knights were down 21-0 at one point in this game, after a Dewayne Coleman to Brady Anderson 68 yard TD on 4th down and a fumble recovery by the defense, Army has a chance to win the game!! pic.twitter.com/qcV5umq0AB
— Im not a fan of your favorite team (@fsh733) September 20, 2025
The Mean Green survived their miscue with a 45-38 overtime win, but Miami (Ohio) and Arkansas weren't as lucky. RedHawks running back Kenny Tracy erased an excellent run in a 38-38 game against the UNLV Rebels (4-0) with a fumble inside the red zone, and the Rebels drove for the winning field goal as time expired in a 41-38 win.
Meanwhile at Yager Stadium, UNLV RECOVERS THE MIAMI (OH) FUMBLE AND HAS A CHANCE TO WIN! pic.twitter.com/XW2o2TzmRi
— Im not a fan of your favorite team (@fsh733) September 20, 2025
Most painfully, Arkansas running back Mike Washington fumbled at the Memphis 9-yard line with 1:22 remaining, preserving the Tigers' victory.
The red zone punchout by Memphis turns over Arkansas
— CJ Fogler (@cjzero.bsky.social) 2025-09-20T19:34:22.101Z
Next time, these teams might want to lean on the pass.
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