Three Associated Press top-five teams bit the dust on Saturday, sending college football into an upheaval entering October.
Here are our winners and losers from a landscape-altering weekend.
Alabama head coach Kalen DeBoer improved to 2-0 against No. 5 Georgia Bulldogs with a 24-21 road win, thanks in part to an awful Kirby Smart decision to forgo a tying field-goal attempt from the Alabama 8-yard line in the fourth quarter. But DeBoer and the Tide deserve credit for once again having a game plan to move the ball against Georgia's defense, scoring all 24 of its points in the first half. Georgia stymied Alabama in the second half, but it was still able to convert in key situations, finishing 13-of-19 on third downs, including a 3rd-and-5 with under two minutes remaining to seal the victory. The Tide might not be the same feared juggernaut they were under retired former coach Nick Saban, but they can still compete with the best.
No. 3 Penn State became the third top-five team to lose when Oregon defensive back Dillon Thieneman intercepted quarterback Drew Allar on the Nittany Lions' first play of the second overtime to preserve a 30-24 win. But its loss was perhaps the most painful, coming after the team had erased a 14-point fourth-quarter deficit. This is also arguably head coach James Franklin's best team, yet it still struggles on the biggest stages.
The redshirt freshman handled his first road start incredibly well, going to Seattle and defeating Washington, 24-6. Sayin was 22-of-28 for 208 yards and two touchdowns, at one point completing 10 consecutive passes as No. 1 Ohio State found a groove late in the second quarter and into the third. Entering October, the Buckeyes look like a legit contender to win a second consecutive College Football Playoff, and Sayin's continued growth is a large reason why.
The second-year starter might be playing himself out of being a high draft pick with his uninspiring start to 2025. In a 24-19 loss to No. 13 Ole Miss, Nussmeier was 21-of-34 for 197 yards, one touchdown and one interception. His accuracy was spotty, and he struggled when extending plays, making more questionable than impressive throws. No. 4 LSU's CFP hopes hinge on Nussmeier turning his season around, but his struggles could have a more long-lasting impact.
Head coach Clark Lea has turned Vanderbilt into a machine. The Commodores notched a 55-35 win over Utah State (3-2), one game after scoring 70 points against Georgia State (1-3). Per ESPN, it's the first time Vanderbilt has scored 50 points in consecutive games in 110 years.
A historic win for Vanderbilt ⚓
— ESPN Insights (@ESPNInsights) September 27, 2025
Next stop: Tuscaloosa pic.twitter.com/q0reGjCpoO
No. 18 Vanderbilt is 5-0 for the first time since 2008. That season, the Commodores peaked at No. 13 in the AP poll after a 14-13 win over then-No. 13 Auburn but went 1-6 over their final seven regular-season games to finish the year unranked. With upcoming games against No. 17 Alabama, No. 4 LSU, No. 20 Missouri and No. 10 Texas, several potential pitfalls remain. However, with the offense firing on all cylinders, Vandy can keep up with anyone it plays.
No. 21 USC was starting to receive some buzz after a 4-0 start, but a 34-32 loss to No. 23 Illinois, which was coming off a 63-10 loss to No. 11 Indiana, showed that it still isn't ready to contend in head coach Lincoln Riley's fourth season. The Trojans gave up 502 yards, and the defense failed to hold onto a late lead by allowing Illinois to drive 51 yards for the winning 41-yard field goal as time expired. In other words, it was the same USC we've come to expect.
A wild weekend of ACC action that began on Friday with No. 8 Florida State's upset road loss at Virginia escalated Saturday with a pair of thrilling comebacks from No. 16 Georgia Tech and Louisville. Both teams erased 17-point deficits in their wins, with the Yellow Jackets coming back from a 20-3 deficit to defeat Wake Forest, 30-29, in overtime. Louisville toppled Pittsburgh, 34-27, after falling into a 17-0 hole in the first quarter. With the wins, the two teams kept pace with Miami as the only undefeated teams remaining in the conference.
Perhaps West Virginia should have left Rodriguez in the past. The Mountaineers became the first Big 12 team with two conference losses on Saturday after losing 48-14 to the Utah Utes. Over its first two Big 12 games, West Virginia has been outscored 89-24, an average of 32.5 points per game. The program had substantial success during Rodriguez's first run as head coach from 2001-07, including three consecutive 10-win seasons, but the reboot is off to a shaky start.
In what was arguably the wildest game of the day, Cincinnati defeated the Kansas Jayhawks, 37-34, in a game that featured 1,200 yards of offense. Cincinnati gained 603 yards, its most on the road as a Big 12 member, and improved to 3-1, already just two wins shy of matching last year's win total. The one-time American Conference power has struggled since moving to the Big 12 in 2023, but Saturday's win was a step in the right direction under third-year head coach Scott Satterfield.
The Razorbacks hit a new low in the Sam Pittman era with a 56-13 home loss to Notre Dame, the first meeting between the two programs. No. 22 Notre Dame led by 29 at halftime and finished with 641 yards, its most since 2017. Afterward, Pittman empathized with fans demanding his firing, telling reporters, "If I was the fans I'd be mad at me, too."
NEW: Sam Pittman sends a message to Arkansas fans wanting him fired:
— On3 (@On3sports) September 27, 2025
"If I was the fans I’d be mad at me too. Hell, I’m mad at me, to be perfectly honest." https://t.co/m1KuTdYMGx pic.twitter.com/yKTW6Z8nCD
It feels like only a matter of time before Pittman is shown the door. When it comes, Saturday's loss to Notre Dame will likely be viewed as the point of no return.
The most exciting quarterback in college football might be the true freshman Keawe-Sagapolutele, who orchestrated a winning drive with under two minutes remaining at Boston College in his first road ACC start.
Keawe-Sagapolutele found tight end Mason Mini for the go-ahead touchdown on a 2nd-and-10, evading pressure while rolling out of the pocket and throwing an accurate pass on the run while approaching the line of scrimmage.
CAL!!! Jaron-Keawe Sagapolutele dime ➡️ Mason Mini for the 51 yard go-ahead TD 1:30 left!! pic.twitter.com/JROSTWBWco
— Im not a fan of your favorite team (@fsh733) September 27, 2025
Expect Keawe-Sagapolutele to get all kinds of offers to enter the transfer portal this offseason. But he's doing okay for himself at Cal, which is 4-1 for the first time since 2019.
Firing DeShaun Foster didn't provide a spark for UCLA, which lost at Northwestern, 17-14, in Week 5. The Bruins are the only winless power conference team and one of just four teams overall, joining Oregon State, Sam Houston and Massachusetts.
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