The San Francisco 49ers had every reason and excuse to lose Thursday's game against the Los Angeles Rams. They were playing on a short week on the road, against a Super Bowl contender and were doing so with a badly depleted lineup that was without several top starters, including quarterback Brock Purdy and some of their biggest pass-catching targets.
Forget just losing, they had every reason to get blown out and entered the game as eight point underdogs.
Not only did they not get blown out, not only did they cover that spread, they actually won the game outright with a 26-23 overtime victory to improve to 4-1 on the season and take over sole possession of first place in the NFC West.
Here are some key takeaways from the 49ers win:
There is not going to be a quarterback controversy in San Francisco because the salaries are not going to allow it. Brock Purdy is making more than $50M per season, is the established starter and is going to keep his job whenever he returns (it could be longer than expected).
That does not mean Mac Jones hasn't been the better quarterback this season. Because he has been.
Jones entered Thursday's game having nearly identical numbers to Purdy this season in the same number of games in the same offense, but with fewer turnovers and interceptions. He only added to that with Thursday's performance where he completed 33-of-49 passes for 342 yards and two touchdowns.
Mac Jones completed 33 of 49 for 342 yards & 2 TDs in the 49ers' overtime win over the Rams.
— Next Gen Stats (@NextGenStats) October 3, 2025
Jones was particularly effective on passes under 10 air yards, finishing 28 of 37 for 258 yards and 2 TDs, the 2nd-most yards in a game on short passes this season.
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He did that with an absolutely depleted lineup that was without Jauan Jennings, Ricky Pearsall and George Kittle, while also playing on a short week. Jones was also playing through an injury of his own, and took a beating on Thursday.
It is only a three-game sample size, but he has outperformed what Purdy did going back to the start of the 2024 season.
They will not start him over a healthy Purdy, but it is probably nice for them to know they have a capable backup that can step in and run Kyle Shanahan's offense incredibly efficiently.
While Jones gave the 49ers a gritty effort, their defense also made two game-changing — and ultimately game-deciding — plays.
The first came late in the fourth quarter when Rams running back Kyren Williams looked to be running in for a go-ahead touchdown. But just before he crossed the goal line, he had the football punched out of his hands by rookie defensive lineman Alfred Collins.
what
— NFL (@NFL) October 3, 2025
a
play
FOOTBALL! pic.twitter.com/fgKXfFU6jF
The Rams ended up getting the ball back and worked their way into field goal range to send the game to overtime.
After San Francisco kicked a field goal on the opening drive of overtime, the Rams again moved down the field on their possession and faced a 4th-and-1 at the San Francisco 11-yard line. Instead of playing for the tie, the Rams tried to get the first down only to have Williams get stuffed on a game-deciding stop.
49ERS GET THE STOP! 49ERS WIN! pic.twitter.com/zw5Hvr25NS
— NFL (@NFL) October 3, 2025
The biggest thing to watch on that 4th-and-1 stop isn't that the Rams went for it (they should have), it's the play-call. After both teams called a timeout, Rams head coach Sean McVay came out and called a run straight up the middle that was stuffed by the 49ers defense.
Why did he take the ball out of quarterback Matthew Stafford's hands at that point? Stafford successfully brought the Rams back from a 14-point deficit on Thursday and has been playing at an MVP level this season. He has been especially sensational the past two weeks, and on Thursday night had thrown for 389 yards, three touchdowns and zero interceptions. It is the second week in a row he topped the 300-yard mark with three touchdowns and zero interceptions, and was on point all night.
Why not let your best player and quarterback make a play with the game on the line? It was just one of the many questionable plays — and mistakes — that the now 3-2 Rams made in a tough divisional loss to a now 4-1 49ers team.
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