Looking ahead to the NFL Week 6 slate, here are five players who need to be in your fantasy football starting lineups.
PPR projection: 19.9
The Ravens can't field a competitive defense right now due to the numerous injuries plaguing their roster. Last week, Houston Texans quarterback C.J. Stroud torched them for 244 passing yards, four touchdowns and 28.76 fantasy points. If the Ravens can't slow down Houston's below-average passing game, Stafford, Puka Nacua and Davante Adams are going to have a field day against this unit.
PPR projection: 13.6
The Bengals traded for Joe Flacco to replace Jake Browning this week, which is great news for Brown. In his four starts with the Browns this season, Flacco sent 8.5 targets per game to his running backs. This should be a busy receiving game for Brown, who's a solid flex play in PPR formats against the Green Bay Packers.
PPR projection: 11.4
Henderson owners have been frustrated by New England's three-man backfield this season, but that's about to change. With running back Antonio Gibson out for the season, Henderson is finally due for an uptick in usage. The rookie RB played a season-high 50 percent of the team's offensive snaps last week, and that number should increase with Gibson out of the lineup. This could be Henderson's breakout game against a Saints defense that ranks 23rd in points allowed to RBs.
PPR projection: 11.7
Calvin Ridley finally had a WR1 game for the 2025 Titans (more pls) https://t.co/8dp4TbNxae pic.twitter.com/x0GOF9zTMo
— Easton Freeze (@eastonfreeze) October 6, 2025
Ridley and quarterback Cam Ward finally found a groove in Week 5, connecting five times on 10 targets for 131 yards against the Arizona Cardinals. If the Titans want to ignite their passing game, they need to keep targeting Ridley down the field. They have a great chance to do just that in Week 6, as the Raiders rank 29th in the NFL in points allowed to wide receivers.
PPR projection: 11.7
Tonges has become a trusty red-zone target for the 49ers with George Kittle on injured reserve. The backup tight end caught seven of his 11 targets for 41 yards and a touchdown against the Rams last week, and he's staring down a great matchup in Week 6. The Buccaneers have already surrendered four red-zone touchdowns to tight ends this year.
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