Marvin Harrison Jr. underwent unexpected surgery

Arizona Cardinals wide receiver Marvin Harrison Jr. Jerome Miron-Imagn Images

Cardinals HC provides update on Marvin Harrison Jr. in wake of appendectomy

Originally posted on Larry Brown Sports
By Steve DelVecchio | Last updated Nov 12, 2025 5:34 PM ET

The Arizona Cardinals will be without Marvin Harrison Jr. in Week 11 and potentially beyond after the star wide receiver had an unexpected surgical procedure.

Cardinals head coach Jonathan Gannon announced on Wednesday that Harrison underwent surgery earlier in the week following a bout of appendicitis.

Harrison will not be able to play in Arizona’s home game against the San Francisco 49ers on Sunday.

When asked if Harrison Jr. could miss more than just one game, Gannon replied, "We'll see," according to NFL.com's Kevin Patra.

Cardinals WR Marvin Harrison Jr. underwent surgery for appendicitis and is out for at least this week and possibly longer.
— Adam Schefter (@AdamSchefter) November 12, 2025

Marvin Harrison Jr. has been having a good season despite questionable QB play

Harrison has been productive in his second NFL season with 525 receiving yards and four touchdowns, but he has yet to top the 100-yard receiving mark through nine games. The former Ohio State star eclipsed that mark just twice as a rookie last year and finished with 885 yards and 8 touchdowns.

The Cardinals have looked better offensively in recent weeks with Kyle Murray on injured reserve and Jacoby Brissett starting for the team. Arizona pulled off an upset win over the Dallas Cowboys in Week 9, and Harrison had a season-high seven catches for 96 yards and a touchdown in that game. The wideout had just three catches for 33 yards and a score in the Cardinals’ 44-22 loss to the Seattle Seahawks on Sunday.

Although an appendectomy is a routine procedure, it is possible Harrison could miss multiple weeks while recovering.

This article first appeared on Larry Brown Sports and was syndicated with permission.

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