New Orleans Saints running back Alvin Kamara. Bob Donnan-Imagn Images

Saints RB Alvin Kamara's career-worst season just managed to get worse

Originally posted on Pro Football Rumors
By Nikhil Mehta | Last updated Nov 29, 2025 1:59 PM ET

New Orleans Saints running back Alvin Kamara suffered a sprained MCL in Week 12 and will miss at least one game.

Kamara went down early in last week’s loss to the Falcons. An MRI revealed he avoided a serious injury, per Nick Underhill of NewOrleans.Football, but he was still ruled out for the Saints’ Week 13 matchup with the Dolphins.

The nine-year veteran should still have a chance to return this season.

2025 has been a down year for Kamara. The five-time Pro Bowler is putting up career-lows across the board with 3.6 yards per carry, 5.6 yards per reception and 59.7 scrimmage yards per game.

Alvin Kamara has an MCL sprain, according to a source. Avoided a major injury, but we'll see how it progresses. He could take a little time, but nothing that's super serious or threatening long term. Hard to know how long. Alvin and his team often beat timelines. https://t.co/qG8LQANY8L
— Nick Underhill (@nick_underhill) November 24, 2025

Who will fill in for Alvin Kamara for the Saints?

Kendre Miller‘s season-ending injury in October will put rookie Devin Neal atop the Saints’ depth chart in Kamara’s absence. The sixth-round pick has appeared in only seven games this season with 29 total touches for 125 yards. In his last three years at Kansas, Neal averaged 6.0 yards per carry and scored 44 total touchdowns.

Kamara’s injury will also get Audric Estime involved after just one appearance and three offensive snaps this year. The 2024 fifth-rounder recorded 310 rushing yards and two touchdowns on 76 carries as a rookie in Denver.

The Saints’ only other running back is Ian Wheeler, a 2023 UDFA who has yet to appear in an NFL game. He will be elevated from the practice squad for Sunday’s game and could have a game-day role until Kamara’s return. New Orleans may also add a veteran to their inexperience, unproven backfield.

This article first appeared on Pro Football Rumors and was syndicated with permission.

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