Eagles get major Saquon Barkley injury update after hamstring setback

Philadelphia Eagles running back Saquon Barkley. IMAGN IMAGES via Reuters Connect

Eagles get major Saquon Barkley injury update after hamstring setback

By Andrew Wright | Last updated Oct 5, 2026 9:15 PM ET

The Philadelphia Eagles may have had the worst loss of any team in Week 5 when they blew a 10-point fourth-quarter lead to the Los Angeles Rams.

Philadelphia's offense struggled to do anything in the game, and that happened as soon as star running back Saquon Barkley exited the game with a hamstring injury.

Barkley was unable to return to Sunday's game, and the timeline for his return from the injury was updated late Monday night.

Saquon Barkley is being listed as week-to-week

According to NFL insiders Ian Rapoport and Mike Garafolo, Barkley is being listed as week-to-week with his hamstring injury. The injury is not expected to be a long-term one, meaning that the hamstring injury is not as serious as some may have feared it was.

Saquon with an apparent injury after the Eagles' last play.

: FOX/FOX One pic.twitter.com/uFXZxBM1pE
— FOX Sports: NFL (@NFLonFOX) October 4, 2026

#Eagles RB Saquon Barkley is considered week-to-week with his hamstring injury, per me and @MikeGarafolo. It’s not considered to be a long-term injury. pic.twitter.com/WvZgowe7Hs
— Ian Rapoport (@RapSheet) October 6, 2026

Saquon Barkley isn't the only injured Eagles running back

To make matters worse for the Philadelphia ground game, backup Tank Bigsby was placed on IR Monday due to needing core muscle surgery.

Bigsby was the workhorse after Barkley exited, as he carried the ball 14 times for 55 yards prior to suffering an injury himself. The hope is that Bigsby will be able to return within six weeks, but that is not a certainty by any means.

#Eagles RB Tank Bigsby suffered an injury on Sunday and now requires core muscle surgery to repair it, sources say. Bigsby is headed to Injured Reserve, with hopes he’s back in six weeks or shorter. pic.twitter.com/LcWgblBpDr
— Ian Rapoport (@RapSheet) October 5, 2026

Who will be the options in Week 5?

Philadelphia will certainly be without Bigsby and likely be without Barkley in Week 5 against the Jacksonville Jaguars.

Will Shipley is the only other running back currently on the 53-man roster, meaning the Eagles will need to elevate someone from the practice squad if Barkley is indeed unable to go on Sunday.

A ground game of Shipley and someone suiting up for Philadelphia for the first time this season will be a tall task to overcome Sunday against a really solid and confident Jaguars team.

Andrew Wright

Andrew "Dew" Wright graduated from Charleston Southern University with a degree in Communication Studies. He is a lifelong Chicago Cubs and Washington Commanders fan.

More must-reads: