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Manchester United vs Chelsea Lineups, Predictions, Team News & Head-to-Head Premier League Stats

Originally posted on Athlon Sports | By Marcelo Cartaxo | Last updated Sep 20, 2025 9:56 AM ET

Manchester United will host Chelsea at Old Trafford on Saturday, September 20, with kickoff set for 12:30 p.m. ET.

United enter the match after a full week of recovery, but the start of their season has been one of the worst in club history: a loss to Arsenal in the opener, an early Carabao Cup exit to a third-division side, a win over Burnley, and a 3-0 defeat to Manchester City where Erling Haaland equaled Wayne Rooney’s derby goal record.

Chelsea, meanwhile, arrive after a 3-1 loss to Bayern Munich in the UEFA Champions League but remain unbeaten in the Premier League with two wins and two draws.

Matheus Cunha and Mason Mount are back in the United squad, though it’s unclear if either will start. Mount, facing his former club, could be key as coach Rúben Amorim faces pressure—another defeat could mark the end of his time at Old Trafford.

Manchester United is up next in the #PL! ✊ pic.twitter.com/zy2dzR6MIi
— Chelsea FC (@ChelseaFC) September 19, 2025

Expected Starting Lineup

Manchester United

Goalkeeper: A. Bayindir
Defenders: L. Yoro, M. de Ligt, L. Shaw
Midfielders: N. Mazraoui, B. Fernandes, Casemiro, P. Dorgu
Wingers: B. Mbeumo, M. Cunha
Forward: B. Sesko

Chelsea

Goalkeeper: R. Sanchez
Defenders: M. Gusto, T. Adarabioyo, T. Chalobah, M. Cucurella
Midfielders: E. Fernandez, M. Caicedo
Attacking midfielders: Estevao, C. Palmer, P. Neto
Forward: J. Pedro

Head-to-Head Stats: Manchester United vs Chelsea

Manchester United and Chelsea have faced each other 193 times in all competitions. United leads the head-to-head with 83 wins, Chelsea has 56 victories, and there have been 54 draws.

At Old Trafford, United’s dominance is clear: the Blues have not won a Premier League game there since 2013.

Recent meetings:

May 2025 – Chelsea 1-0 Man United
Nov 2024 – Chelsea 1-1 Man United
Apr 2024 – Chelsea 4-3 Man United

Across their last 10 encounters, United has 3 wins, Chelsea has 2 wins, and there have been 5 draws.

In terms of goals, matches between these two sides usually see both teams scoring — with an average of around 2.5 goals per game over the last five clashes.

This article first appeared on Athlon Sports and was syndicated with permission.

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