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When you have a conference with 16 teams, someone has to struggle. At the moment, that's South Carolina, and Kentucky is a loss away from being thrown in that bucket.
The Gamecocks have an NFL quarterback in LaNorris Sellers, a ton of experience, and through-the-roof expectations that went bye-bye over the last two weeks in losses to Vanderbilt and Missouri.
Lose here, and with LSU, Oklahoma, Alabama, Ole Miss, and Texas A&M coming up next, forget the CFP and the SEC race, just getting to a bowl will be tough.
Kentucky wasn't bad in the loss to Ole Miss, and it's still just 2-1 and rested after an off week, but there's a trip to Georgia next week, followed by Texas, Tennessee, and a date at Auburn.
Kentucky vs South Carolina Game Preview
Kentucky vs South Carolina How To Watch
Saturday, September 27, 2025
Game Time: 7:45 PM ET
TV: SEC Network
Location: Williams-Brice Stadium, Columbia, SC
@PeteFiutak
Why Kentucky Will Win
It's had two weeks off to get ready, and it's not in crisis mode like South Carolina is.
There's that sense of urgency around the Gamecocks that only comes from losing two straight conference games in September. They'll be pressing, and so far, that hasn't worked.
What's the problem? South Carolina looks like a team that's playing with the weight of the world on its shoulders.
Converting on third downs seems impossible, the penalties are flowing, and Sellers hasn't been able to find a groove because the offensive line is letting everyone live in the backfield.
Kentucky has to score early, and ramp that in-house pressure up even more.
Why South Carolina Will Win
LaNorris Sellers, you're a future franchise-maker for some NFL city. This is where it starts.
The last two weeks have hardly been his fault. He's getting the ball down the field, and he's trying to make things happen despite getting knocked out of the Vanderbilt loss, but he needs help.
The Kentucky secondary got torched by Eastern Michigan, Ole Miss ran the ball too easily, and it's all because the Kentucky line doesn't generate any pressure. As long as South Carolina can take a deep breath and make the plays that are there ...
Will the Real South Carolina Please Show Up?
The team is better than this.
The Vanderbilt loss seemed to throw everyone for a loop, but this is where Sellers should shine. Now it's about whether or not the Gamecock lines step up.
Kentucky will run a little too easily on the South Carolina front, but after the Missouri game, the Gamecock defense will step up its play a bit.
And then it'll be up to 16 to save the day.
Kentucky vs South Carolina Prediction, Betting Lines
South Carolina 30, Kentucky 24
Line: South Carolina -6.5, o/u: 46.5
ATS Confidence out of 5: 2.5
Must See Rating: 3
Consensus Line from BetMGM, Caesars, DraftKings, and FanDuel. Game odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.
More must-reads:
- Three CFB teams on upset alert in Week 5
- Urban Meyer takes shot at Bill Belichick and North Carolina
- The 'Multiple 10-sack NFL seasons' quiz
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