UCLA vs Indiana Prediction: Bruins Try to Stay Hot Against Hoosiers

How To Watch UCLA vs Indiana

Saturday, October 25, 2025
Game Time: 3:30 PM ET
TV: FOX
Location: Memorial Stadium, Bloomington, IN

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Why UCLA Will Win

What’s UCLA doing so right over the last three games? The offensive line play is better, but the revamped coaching staff is leaning into the ground game and letting it work.

The Bruins were effective on the ground over the first four games, but it never came up with more than 30 carries. It’s busting out an average of 44 carries a game over the last three.

The Indiana run defense might be fantastic, but the Bruins can’t be afraid to stick with it. They have to do everything possible to control the tempo and not let the Hoosiers dominate the time of possession battle. However …

Why Indiana Will Win

Indiana has a funky way of making teams blow off their game plans.

Things might be going well for the Bruins, but they’re still having massive issues generating third down stops. Indiana doesn’t need to hit the home runs. They can grind, connect on the short-to-midrange throws, and take over the game early on.

UCLA was able to stop Michigan State and Maryland from connecting on anything - the two combined for under 50% completion rate. Indiana doesn’t miss, it’ll push the UCLA secondary from the start, and …

UCLA vs Indiana Prediction, Betting Lines

UCLA is playing with house money.

It turned around its season with three great wins, and the loose and fearless style matters. Indiana isn’t the type of team that plays like it's under pressure, but the Bruins should bust out enough of a ground game early on to make this an interesting dynamic.

The lack of pressure from the UCLA defensive front will matter. It might take a quarter, but Fernando Mendoza will get into a groove, the Indiana tempo will take over, and UCLA won’t be able to stop it.

It won’t be a total wipeout, but the Hoosiers will keep on rolling.

Indiana 38, UCLA 13
Line: UCLA -25.5, o/u: 54.5
ATS Confidence out of 5: 2
Must See Rating: 3.5
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Consensus Line from BetMGM, Caesars, DraftKings, and FanDuel. Game odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.

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