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Week 2 of the 2025 college football season features 83 games from Friday, Sept. 5 through Saturday night on Sept. 6. Athlon Sports is back with predictions and picks for every contest.
The second full weekend of the '25 season starts with four contests on Friday night, including James Madison at Louisville and Northern Illinois visiting Maryland.
A busy schedule of games is on tap for Saturday this week. Illinois-Duke, Iowa-Iowa State, Baylor-SMU, Virginia-NC State, and UConn-Syracuse headline the top contests in the first window. The afternoon slate includes Kansas-Missouri, Ole Miss-Kentucky, Fresno State-Oregon State, Oklahoma State-Oregon, South Florida-Florida, and Arkansas State-Arkansas.
The first night window is headlined by Army-Kansas State, Arizona State-Mississippi State, Michigan-Oklahoma, Boston College-Michigan State, and Vanderbilt-Virginia Tech. The late-night portion of the Week 2 schedule features San Diego State-Washington State, Stanford-BYU, and Sam Houston-Hawaii.
College Football Picks: Expert Predictions for Every Game in Week 2
Steven |
Thomas |
Kyle |
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James Madison |
@ Louisville |
Louisville |
Louisville |
Louisville |
Western Illinois |
@ Northwestern |
Northwestern |
Northwestern |
Northwestern |
Northern Illinois |
@ Maryland |
Maryland |
Maryland |
Maryland |
Eastern Washington |
@ Boise State |
Boise State |
Boise State |
Boise State |
Northern Colorado |
@ Colorado State |
Colorado State |
Colorado State |
Colorado State |
Sacramento State |
@ Nevada |
Nevada |
Nevada |
Nevada |
Idaho State |
@ New Mexico |
New Mexico |
New Mexico |
New Mexico |
San José State |
@ Texas |
Texas |
Texas |
Texas |
Florida International |
@ Penn State |
Penn State |
Penn State |
Penn State |
Illinois |
@ Duke |
Illinois |
Illinois |
Duke |
Baylor |
@ SMU |
Baylor |
Baylor |
SMU |
Kennesaw State |
@ Indiana |
Indiana |
Indiana |
Indiana |
Iowa |
@ Iowa State |
Iowa State |
Iowa State |
Iowa State |
Kent State |
@ Texas Tech |
Texas Tech |
Texas Tech |
Texas Tech |
Northwestern State |
@ Minnesota |
Minnesota |
Minnesota |
Minnesota |
Virginia |
@ NC State |
NC State |
Virginia |
NC State |
Central Michigan |
@ Pittsburgh |
Pitt |
Pitt |
Pitt |
UConn |
@ Syracuse |
Syracuse |
Syracuse |
Syracuse |
East Texas A&M |
@ Florida State |
Florida Staet |
Florida State |
Florida State |
Liberty |
@ Jacksonville State |
Liberty |
Liberty |
Jacksonville State |
Utah State |
@ Texas A&M |
Texas A&M |
Texas A&M |
Texas A&M |
Western Carolina |
@ Wake Forest |
Wake Forest |
Wake Forest |
Wake Forest |
Howard |
@ Temple |
Temple |
Temple |
Temple |
Grambling |
@ Ohio State |
Ohio State |
Ohio State |
Ohio State |
Troy |
@ Clemson |
Clemson |
Clemson |
Clemson |
Austin Peay |
@ Georgia |
Georgia |
Georgia |
Georgia |
Oklahoma State |
@ Oregon |
Oregon |
Oregon |
Oregon |
Ole Miss |
@ Kentucky |
Ole Miss |
Ole Miss |
Ole Miss |
East Tennessee State |
@ Tennessee |
Tennessee |
Tennessee |
Tennessee |
Kansas |
@ Missouri |
Missouri |
Missouri |
Missouri |
Miami (OH) |
@ Rutgers |
Rutgers |
Rutgers |
Rutgers |
Fresno State |
@ Oregon State |
Oregon State |
Oregon State |
Fresno State |
Gardner-Webb |
@ Georgia Tech |
Georgia Tech |
Georgia Tech |
Georgia Tech |
Bowling Green |
@ Cincinnati |
Cincinnati |
Cincinnati |
Cincinnati |
Delaware |
@ Colorado |
Colorado |
Colorado |
Colorado |
Lindenwood |
@ App State |
App State |
App State |
App State |
Texas State |
@ UTSA |
UTSA |
Texas State |
UTSA |
UAB |
@ Navy |
Navy |
Navy |
Navy |
North Texas |
@ Western Michigan |
North Texas |
Western Michigan |
North Texas |
Saint Francis |
@ Buffalo |
Buffalo |
Buffalo |
Buffalo |
Bryant |
@ Massachusetts |
UMass |
UMass |
UMass |
Middle Tennessee |
@ Wisconsin |
Wisconsin |
Wisconsin |
Wisconsin |
West Virginia |
@ Ohio |
West Virginia |
West Virginia |
Ohio |
Northern Iowa |
@ Wyoming |
Wyoming |
Wyoming |
Wyoming |
South Florida |
@ Florida |
Florida |
Florida |
Florida |
Arkansas State |
@ Arkansas |
Arkansas |
Arkansas |
Arkansas |
Jackson State |
@ Southern Miss |
Southern Miss |
Southern Miss |
Southern Miss |
Texas Southern |
@ California |
California |
California |
California |
Cal Poly |
@ Utah |
Utah |
Utah |
Utah |
Missouri State |
@ Marshall |
Marshall |
Marshall |
Marshall |
North Carolina Central |
@ Old Dominion |
Old Dominion |
Old Dominion |
Old Dominion |
Campbell |
@ East Carolina |
ECU |
ECU |
ECU |
Florida A&M |
@ Florida Atlantic |
FAU |
FAU |
FAU |
Bethune-Cookman |
@ Miami |
Miami |
Miami |
Miami |
South Carolina State |
@ South Carolina |
South Carolina |
South Carolina |
South Carolina |
Army |
@ Kansas State |
Kansas State |
Kansas State |
Kansas State |
North Carolina |
@ Charlotte |
UNC |
UNC |
UNC |
Houston |
@ Rice |
Houston |
Houston |
Rice |
North Carolina A&T |
@ UCF |
UCF |
UCF |
UCF |
Western Kentucky |
@ Toledo |
Toledo |
Toledo |
WKU |
Memphis |
@ Georgia State |
Memphis |
Memphis |
Memphis |
Tulane |
@ South Alabama |
Tulane |
Tulane |
Tulane |
Long Island University |
@ Eastern Michigan |
Eastern Michigan |
Eastern Michigan |
Eastern Michigan |
Louisiana Tech |
@ LSU |
LSU |
LSU |
LSU |
Arizona State |
@ Mississippi State |
Arizona State |
Arizona State |
Arizona State |
Michigan |
@ Oklahoma |
Oklahoma |
Michigan |
Oklahoma |
Ball State |
@ Auburn |
Auburn |
Auburn |
Auburn |
Vanderbilt |
@ Virginia Tech |
Vanderbilt |
Vanderbilt |
Virginia Tech |
Akron |
@ Nebraska |
Nebraska |
Nebraska |
Nebraska |
Georgia Southern |
@ USC |
USC |
USC |
USC |
Boston College |
@ Michigan State |
Michigan State |
Michigan State |
Boston College |
Southern Illinois |
@ Purdue |
Purdue |
Purdue |
Purdue |
Charleston Southern |
@ Coastal Carolina |
Coastal Carolina |
Coastal Carolina |
Coastal Carolina |
UL Monroe |
@ Alabama |
Alabama |
Alabama |
Alabama |
UCLA |
@ UNLV |
UCLA |
UCLA |
UNLV |
McNeese |
@ Louisiana |
Louisiana |
Louisiana |
Louisiana |
Tulsa |
@ New Mexico State |
Tulsa |
Tulsa |
Tulsa |
UT Martin |
@ UTEP |
UTEP |
UTEP |
UTEP |
Weber State |
@ Arizona |
Arizona |
Arizona |
Arizona |
San Diego State |
@ Washington State |
Washington State |
SDSU |
Washington State |
Stanford |
@ BYU |
BYU |
BYU |
BYU |
UC Davis |
@ Washington |
Washington |
Washington |
Washington |
Sam Houston |
@ Hawai'i |
Hawaii |
Hawaii |
Hawaii |
Week 1 |
Record |
82-9 |
78-13 |
78-13 |
Season |
Record |
86-10 |
82-14 |
82-14 |
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- Justin Fields, former college teammate showcase renewed chemistry vs. Steelers
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