Oneil Cruz and Shohei Ohtani (Photos by Imagn Images)

Top 5 MLB Home Run Predictions Today: Exclusive Picks For April 13, 2026

Originally posted on Total Pro Sports | By Heena Singh | Last updated Apr 13, 2026 12:39 PM ET

April 13 brings another loaded MLB slate, and the long ball is already heating up across the league. Early-season trends are starting to settle, and a few elite bats are beginning to separate themselves with consistent power output. With favorable matchups on deck, tonight’s board is packed with legit home run threats. Here’s a clean look at the top five picks to go yard.

Top 5 MLB Home Run Prop Bets For April 13, 2026

5) Oneil Cruz +511

Oneil Cruz (Image Credits: Imagn)

Cruz is turning into a nightly home run threat. The Pirates slugger already has five bombs in just over two weeks and is coming off a homer in his last outing. His elite exit velocity makes him dangerous against any pitching staff, and facing Washington gives him a real shot to cash at long odds.

4) Gunnar Henderson +436

Gunnar Henderson (Image Credit/Imagn)

Henderson’s power surge looks very real. With six home runs already this MLB season, he’s sitting near the top of the league leaderboard. Arizona’s pitching staff has been vulnerable to lefty power, and Henderson’s aggressive approach at Camden Yards keeps him firmly in play tonight.

3) Corey Seager +394

Corey Seager (Image Credits: Imagn)

This one has a little storyline juice. Seager heads back to Dodger Stadium, and he’s already swinging it well with four homers this MLB season. He thrives in big moments, and this interleague matchup sets up perfectly for him to leave the yard against his former squad.

2) Ronald Acuña Jr. +355

Ronald Acuna Jr. (Image Credits: Imagn)

Acuña hasn’t fully unleashed his power yet, but the underlying metrics say it’s coming. He’s crushing the ball with elite hard-hit rates and riding a strong on-base streak. Miami’s pitching could be the spot where he finally breaks through in a big way.

1) Shohei Ohtani +254

Shohei Ohtani (Photo Via Imagn Images)

Ohtani remains the safest bet on the board. He’s already homered in three of his last seven MLB games and continues to produce at an MVP level. Facing the Mets, his combination of power, plate discipline, and current form makes him the top pick to go deep tonight.

This article first appeared on Total Pro Sports and was syndicated with permission.

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