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Top MLB DFS Start‘em/Sit‘em For August 22nd
- Apr 11, 2025; Phoenix, Arizona, USA; Milwaukee Brewers second base Brice Turang (2) celebrates with catcher William Contreras (24) after scoring in the fifth inning against the Arizona Diamondbacks at Chase Field. Mandatory Credit: Matt Kartozian-Imagn Images

The weekend is here, and fantasy players could win big in tonight’s top MLB DFS lineups and cash prizes. Friday’s 15-game slate will start the weekend in style and could help players win cash prizes. With August ending in two weeks, fantasy players could win cash prizes to start the weekend with a bang.

Friday’s games will kick off the weekend with a strong slate of games, including the classic rivalry of the Boston Red Sox and the New York Yankees. Another game that could end the week wi th a bang is the Atlanta Braves’ starting a weekend series against the New York Mets with playoff implications tonight.

The weekend is heating up the MLB season before the end of August, and fantasy players could win cash prizes to start the weekend with a bang. 

August 22nd Top MLB DFS Lineup Starters 

3B Eugenio Suarez, Athletics at Seattle Mariners ($4,900 – DraftKings/3,400-Fanduel)

To start Friday night’s top MLB DFS lineups, Eugenio Suarez, of the Seattle Mariners, should be in your lineups. Durin g a crushing loss against the Phillies, Suarez went 1-4 with three strikeouts, an RBI, and a home run. 

Suarez, while struggling, could find his groove against the Athletics tonight. Fantasy players could see a home run from the Mariners’ star slugger against a weak Athletics pitching staff tonight. 

1B Matt Olson, New York Mets at Atlanta Braves ($4,800 – DraftKings/3,400-Fanduel)

Matt Olson of the Atlanta Braves should be in Friday night’s top MLB DFS lineups for fantasy players. In the win against the White Sox, Olson went 0-4 with a strikeout. 

Olson has been playing well against the Mets this season and could have another strong game tonight. Fantasy players could expect a multi-RBI ga me from the Braves star slugger tonight to start the weekend top MLB DFS lineups. 

2B Matt McLain, Cincinnati Reds at Arizona Diamondbacks ($3,900 – DraftKings/2,800-Fanduel)

The last player to have for your fantasy lineups is Matt McLain, of the Cincinnati Reds, in tonight’s top MLB DFS lineups. In a loss against the Angels, McLain went 1-3 with a strikeout during a brutal loss against the Angels. 

McLain has been playing well this season and could have a bounce-back game against the Diamondbacks. Tonight’s top MLB DFS lineup players could see a multi-hit game from the Reds star infielder. 

August 22nd Top MLB DFS Benchwarmers 

SS Bobby Witt Jr, Kansas City Royals at Detroit Tigers ($5,600 – DraftKings/3,900-Fanduel) 

Bobby Witt Jr is the first player who should be on your top MLB DFS fantasy benches for Friday night’s games. During a win against the Rangers, Witt went 2-5 with a double and two stolen bases. 

Witt has been playing well for the Royals this season, but could have a rough game against the Tigers’ pitching staff tonight. Fantasy players could see a multi-strikeout game from the Royals superstar against a division rival. 

OF Corbin Carroll, Cincinnati Reds at Arizona Diamondbacks ($6,300 – DraftKings/4,100-Fanduel)

Corbin Carroll of the Arizona Diamondbacks is another player who should be on your fantasy bench in tonight’s Top MLB DFS lineups. In a win against the Guardians, Carroll went 1-4 with a strikeout. 

Carroll has been playing well this season, but could have a rough game against the Reds’ strong pitching staff tonight. Fantasy lineup players could expect a multi-strikeout game from the Diamondbacks’ star outfielder against a solid Reds pitching staff tonight. 

OF Kyle Tucker, Chicago Cubs at Los Angeles Angels ($5,400 – DraftKings/3,600-Fanduel) 

Kyle Tucker of the Chicago Cubs should be the last player on your top MLB DFS bench for Friday night’s games. In the loss against the Brewers, Tucker went 0-4 with a walk during a brutal loss at Chicago. 

Tucker has been having a nightmare August, and could have another poor game for the Cubs against the Angels. Fantasy players could see a multi-strikeout game from the Cubs’ All-Star against the Angels tonight. 

Total Apex Media Stack Of The Day

Jun 27, 2025; Milwaukee, Wisconsin, USA; Milwaukee Brewers right fielder Sal Frelick (10) drives in a run during the fourth inning against the Colorado Rockies at American Family Field. Mandatory Credit: Jeff Hanisch-Imagn Images

Friday’s top MLB DFS stack should be the Milwaukee Brewers, Sal Frelick, Isaac Collins, and William Contreras. The Brewers have been one of the hottest teams in the MLB and could have another strong game for fantasy players tonight. Tonight’s top MLB DFS stack s should have the Brewers in their fantasy lineup games. 

The first player to have in tonight’s top MLB DFS stack is Frelick, who is having a strong season for the Brewers. In the win against the Cubs, Frelick went 2-4 with a double and a run in the close victory. Frelick has been having a strong season for the Brewers and could have another great performance tonight. Fantasy players could see a multi-hit game from the Brewers’ emerging star outfielder tonight. 

Another player who could have a strong game for fantasy players tonight is Collins, who has been breaking out this year. During the win against the Cubs, Collins went 1-4 with two RBIs and a stolen base. Collins has been having a strong season for the Brewers, and could have another great game tonight. DFS players could see a multi-hit game from the Bre wers’ emerging star outfielder against the Giants tonight.

The last player to have in tonight’s top MLB DFS stack is Contreras, who is having another solid season for the Brewers. In the winning effort against the Cubs, Contreras went 0-3 with a walk and a strikeout. Contreras has been playing better in the second half of the season and could have a strong night for fantasy lineups. DFS players could see a multi-hit game from the Brewers’ star catcher against the Giants tonight. The weekend is here, and fantasy players could kick it off right with tonight’s top MLB DFS lineups and stacks and win cash prizes.

This article first appeared on Total Apex Fantasy Sports and was syndicated with permission.

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