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Top MLB DFS Start‘em/Sit‘em For September 28th
- Jun 27, 2025; Boston, Massachusetts, USA; Toronto Blue Jays first baseman Vladimir Guerrero Jr. (27) high-fives shortstop Bo Bichette (11) after scoring a run on a walk during the seventh inning against the Boston Red Sox at Fenway Park. Mandatory Credit: Brian Fluharty-Imagn Images

Today is the end of the MLB regular season, and fantasy players could win cash prizes in today’s top MLB DFS lineups and fantasy stacks to end the season before the postseason. Sunday’s 15-game slate will end the season and weekend with a flurry of games for fantasy players to end another season. With the season ending today, fantasy players could win cash prizes in today’s top MLB DFS lineups and fantasy stacks this Sunday afternoon. 

Sunday’s games will end the weekend and the season with a bang, with the Cincinnati Reds taking on the Brewers, and potentially clinching a wild card spot today.  Another game that could help fantasy players win cash prizes in tonight’s top MLB DFS lineups and stacks is the Miami Marlins’ ending their regular season against the Mets in hopes of spoiling their season to end the weekend. 

With the MLB season ending today, fantasy players could win cash prizes in today’s slate of games and end the season with a bang in today’s top MLB DFS lineups and fantasy stacks. 

September 28th Top MLB DFS Lineup Starters 

SS Otto Lopez, New York Mets at Miami Marlins ($3,400 – DraftKings/3,000-Fanduel)

To start Sunday afternoon’s top MLB DFS lineups, Otto Lopez of the Miami Marlins should be in your lineups. In the shutout loss to the Mets, Lopez went 0-3 during a brutal loss to their rivals. 

Lopez could have a bounce-back game against the Mets, in which he has been hitting well this season. With a chance to spoil the Mets’ postseason chances, Lopez could have a multi-RBI game with a potential home run.

2B/SS Ernie Clement, Tampa Bay Rays at Toronto Blue Jays ($3,100 – DraftKings/2,600-Fanduel)

Ernie Clement of the Toronto Blue Jays should be in Sunday afternoon’s top MLB DFS lineups for fantasy players. In the crushing win against the Rays, Clement went 2-3 with two runs, a double, two RBIs, and a stolen base. 

Clement has been having a breakout season and could have another strong performance. Fantasy players could see a multi-RBI game from the Blue Jays’ emerging star against a poor Tampa Rays pitching staff. 

OF Jackson Merrill, Arizona Diamondbacks at San Diego Padres ($4,400 – DraftKings/3,300-Fanduel)

The last player to have for your fantasy lineups is Jackson Merrill, of the San Diego Padres, in this afternoon’s top MLB DFS lineups. In the win against the Diamondbacks, Merrill went 0-4 with a strikeout. 

Merrill has been playing well this season, even with injuries, and could have a strong game to end the season. DFS players could see a multi-home run game from the Padres’ emerging superstar against their division rivals. 

September 28th Top MLB DFS Benchwarmers 

3B Junior Caminero, Tampa Bay Rays at Toronto Blue Jays ($5,500 – DraftKings/3,700-Fanduel)

Junior Caminero is the first player who should be on your top MLB DFS fantasy benches for Sunday afternoon’s games. In the loss to the Blue Jays, Caminero went 2-3 with a walk and a strikeout. 

Caminero has been having a rough September and could end it with another whimper. Fantasy players could see a multi-strikeout game from the Rays’ standout emerging star to end his season for fantasy lineups.

1B Andrew Vaughn, Cincinnati Reds at Milwaukee Brewers ($3,400 – DraftKings/2,900-Fanduel)

Andrew Vaughn of the Milwaukee Brewers is another player who should be on your fantasy bench in this afternoon’s Top MLB DFS lineups. In the crushing defeat against the Reds, Vaughn went 0-3 with a run and a walk. 

Vaughn has been struggling recently and could have another poor performance today. DFS players could see a multi-strikeout, along with a hitless game, to end the season for fantasy lineups.  

OF Brandon Nimmo, New York Mets at Miami Marlins ($4,000 – DraftKings/3,200-Fanduel) 

Brandon Nimmo of the New York Mets should be the last player on your top MLB DFS bench for Sunday afternoon’s games. In an inspiring win against the Marlins, Nimmo went 1-4 with a walk and three strikeouts. 

Nimmo, while having a career year, is struggling and could have a weak game that could cost the Mets a postseason spot. Fantasy players could see another multi-strikeout game from the Mets veteran star.

Total Apex Media Stack Of The Day

Aug 19, 2025; Pittsburgh, Pennsylvania, USA; Toronto Blue Jays right fielder Addison Barger (right) greets designated hitter George Springer (4) crossing home plate on a two run home run against the Pittsburgh Pirates during the second inning at PNC Park. Mandatory Credit: Charles LeClaire-Imagn Images

Sunday’s top MLB DFS stack should be the Toronto Blue Jays, George Springer, Vladimir Guerrero Jr, and Daulton Varsho. The Blue Jays are close to clinching an American League East championship and could do so today, which would help players win cash prizes. With the AL East on the line, fantasy players could win cash prizes with the Blue Jays lineup to end the MLB season. 

The first player for today’s top MLB DFS stack to end the MLB season should be Springer, who is having a strong season for the Blue Jays. In the win against the Rays, Springer went 1-3 with a walk and a strikeout. Springer has been having a comeback season after an injury-riddled 2024 and could end the season strong. Fantasy players could see a multi-RBI game from the Blue Jays veteran, which could help players win cash prizes. 

Another player who could have a strong finish to the MLB season is Vladimir Guerrero Jr, who is having another great season. In the win against the Tampa Bay Rays, Guerrero went 0-4 with a strikeout. Vlad Jr has been having a strong season for the Blue Jays and could end the season with a bang, helping fantasy players win cash prizes in today’s lineup games. DFS players could see a multi-home run game from the Blue Jays superstar slugger and could win the division, along with fantasy cash prizes. 

The last player for tonight’s top MLB DFS lineup stack is Varsho, who could have a great game against the Rays to end the season. In the crushing win against the Rays, Varsho went 0-3 with a strikeout. Varsho has been having a solid season for the Blue Jays and could have another solid performance against the Rays today. DFS players could expect a multi-hit game from the Blue Jays veteran outfielder. With the MLB season ending today, fantasy players could end it with a bang with today’s top MLB DFS lineups and stacks.

This article first appeared on Total Apex Fantasy Sports and was syndicated with permission.

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