2025 NFL Week 10 Preview & Predictions

The Broncos are on a heater after starting the season 1-2 and winning their last six straight games. The defense is playing up to expectations, and Bo Nix is becoming a fourth-quarter master.

The Raiders just traded Jakobi Meyers away and are likely heading toward another rebuild. This is a Thursday night division game, so anything could happen. It’s hard to bet against Denver, though.

Winner: Denver Broncos

Atlanta Falcons (3-5) Vs. Indianapolis Colts (7-2)

Daniel Jones and the Colts had cold water poured on them in a loss to the Pittsburgh Steelers. They are, however, seemingly unfazed by this and made a win-now trade for cornerback Sauce Gardner at the deadline.

The Falcons are wildly inconsistent in 2025, and it’s hard to tell which version will show up on Sunday. Indy is looking for a bounce-back game against a mediocre opponent.

Winner: Indianapolis Colts

New Orleans Saints (1-8) @ Carolina Panthers (5-4)

The Panthers are surprisingly above .500 in November. The defense is playing well, Bryce Young isn’t making mistakes, and Rico Dowdle has taken over the RB1 spot. Maybe this team isn’t such a joke after all.

The Saints just traded away Rashid Shaheed. 2025 is a wash for them, and they’re already looking to next year. Rookie QB Tyler Shough’s development is interesting, but may be for nothing in the end.

Winner: Carolina Panthers

New York Giants (2-7) @ Chicago Bears (5-3)

It’s amazing what good coaching can do. The Bears are coming off a 47-42 win over the Cincinnati Bengals. Caleb Williams is slowly realizing his potential with Ben Johnson, and they’re facing a team that’s on the verge of imploding.

The Giants’ defense is toast, and rookie QB Jaxson Dart has no true playmakers to throw to. This season feels over for Big Blue, and it’s hard to imagine they’ll keep up with a hot Bears team.

Winner: Chicago Bears

Jacksonville Jaguars (5-3) @ Houston Texans (3-5)

The Texans’ defense is top-notch, while the offense is lucky to make any kind of impact. Now, with C.J. Stroud’s status in the air, they might be in even worse shape.

The Jaguars just traded for Jakobi Meyers and are looking to take a shot at the playoffs. They’re frisky and fun, while the Texans are just hard to watch.

Winner: Jacksonville Jaguars

Buffalo Bills (6-2) @ Miami Dolphins (2-7)

This feels like a huge trap game after the Bills beat the Kansas City Chiefs. Buffalo looked complete in every phase of the game, but now James Cook is nursing a minor leg injury.

The Dolphins are coming off a Thursday night beatdown by the Baltimore Ravens. Every week feels like a question of when they’ll hit the reset button. The Bills are the obvious pick here, but anything can happen in a divisional game.

Winner: Buffalo Bills

Baltimore Ravens (3-5) @ Minnesota Vikings (4-4)

Are the J.J. McCarthy-led Vikings good? It’s certainly too soon to say, but they executed a perfect game plan against the Detroit Lions. This team might not be out of the race yet.

The Ravens need this win more than anything. Baltimore wants to make a playoff push after a rough start to the season. Expect Lamar Jackson to come out swinging here.

Winner: Baltimore Ravens

Cleveland Browns (2-6) @ New York Jets (1-7)

The Jets are officially looking to the future after offloading Sauce Gardner and Quinnen Williams for multiple draft picks. They might be in full tank mode now.

The Browns are, unfortunately, not much better off. They’re still seeing what rookie QB Dillon Gabriel can do, but may turn to Shedeur Sanders at some point. Cleveland has a solid defense, and that might be the reason they win.

Winner: Cleveland Browns

New England Patriots (7-2) @ Tampa Bay Buccaneers (6-2)

The Buccaneers are coming off a desperately needed bye week here. They’ve been dealing with injuries all year, but are still in the race. This will be a big test for Baker Mayfield and co.

The Patriots are wildly fun to watch in 2025. Drake Maye is an MVP candidate, the defense is showing up, and Mike Vrabel might win coach of the year. This is a toss-up, but New England has the hot hand here.

Winner: New England Patriots

Arizona Cardinals (3-5) @ Seattle Seahawks (6-2)

The Cardinals are rolling with veteran QB Jacoby Brissett for this week’s matchup. Kyler Murray has been placed on injured reserve, and will miss at least the next four weeks.

The Seahawks are officially in win-now mode after acquiring receiver Rashid Shaheed. Sam Darnold is a franchise QB, Jaxon Smith-Njigba is going crazy, and the defense is sneaky good. Seattle might make a real run this year.

Winner: Seattle Seahawks

Los Angeles Rams (6-2) @ San Francisco 49ers (6-3)

Keeping things in the NFC West, the Rams and 49ers also have six wins each. Los Angeles has an offense that can light up the scoreboard on any given week. They’re facing a depleted defense on Sunday.

The 49ers are still dealing with injuries to top stars. While it’s unclear if Brock Purdy will play, Mac Jones has been stepping up to the challenge. This is a tough game to call, but the Rams are simply healthier.

Winner: Los Angeles Rams

Detroit Lions (5-3) @ Washington Commanders (3-6)

The Lions have not lost two consecutive games since October 30, 2022. They’re coming off an upset loss to a division rival and now facing a battered opponent.

The Commanders are now without Marshon Lattimore, Luke McCaffrey, and Jayden Daniels, among other injuries. 2025 is just about over for this team, especially with their remaining schedule.

Winner: Detroit Lions

Pittsburgh Steelers (5-3) @ Los Angeles Chargers (6-3)

The Steelers finally looked the way fans expected in a victory over the Colts. The defense played tough, and everything looked easier for them out there. Simplifying things might just be the answer.

The Chargers are once again without Joe Alt. Losing one offensive lineman doesn’t always turn the tide, but along with all their other injuries, this one hurts. Justin Herbert is good, but Pittsburgh might have figured it out.

Winner: Pittsburgh Steelers

Philadelphia Eagles (6-2) @ Green Bay Packers (5-2-1)

The Eagles have made some great trade moves this season, now acquiring Jaelan Phillips from the Miami Dolphins. They’re playing well again and coming off a well-timed bye week.

The Packers are either a Super Bowl contender or just a bad football team. They lost to the Panthers at home 16-13 and are now without star tight end Tucker Kraft for the season. It’s hard to give them any confidence on a weekly basis.

Winner: Philadelphia Eagles

End Of My NFL Rant

November football is supremely important for teams making a run. Schedules are getting tougher for some, while others are entering a favorable stretch. This is when the playoff picture truly takes shape.