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49ers rumored to open the 2025 season on the road vs. Seahawks

Originally posted on 49ers Webzone | By David Bonilla | Last updated May 13, 2025 6:47 PM ET

The NFL is set to release its full 272-game regular-season schedule for 2025 on Wednesday at 5:00 p.m. PT. However, Seattle-area radio host Dave "Softy" Mahler may have already revealed the San Francisco 49ers' Week 1 opponent. According to Mahler, head coach Kyle Shanahan and the 49ers will open the season with an NFC West showdown at Lumen Field against the Seattle Seahawks on Sunday, September 7.

Hearing the Seahawks will open the season vs the 49ers at home on 9/7
Official announcement comes tomorrow
— Dave "Softy" Mahler (@Softykjr) May 13, 2025

If accurate, this would mark the fourth time in the past five seasons that the 49ers begin their schedule on the road. It would also be their first Week 1 matchup against the Seahawks since 2011, and their first opener against an NFC West opponent since 2020.

The 49ers are coming off a disappointing 6-11 season, finishing last in the NFC West and missing the playoffs for the first time since 2020. The Seahawks, meanwhile, ended 2024 with a 10-7 record, finishing second in the division behind the Los Angeles Rams.

We'll find out on Wednesday if Mahler's report proves accurate when the league's official schedule is revealed.

This article first appeared on 49ers Webzone and was syndicated with permission.

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