49ers select CB Ephesians Prysock in 4th round of 2026 NFL Draft

The San Francisco 49ers selected Washington cornerback Ephesians Prysock with the 39th pick (No. 139 overall) in the fourth round of the 2026 NFL Draft.

Prysock split four collegiate seasons between Arizona and Washington, totaling 170 tackles, 20 passes defensed, and two interceptions across 49 games (42 starts). During his senior season at Washington in 2025, he earned honorable-mention All-Big Ten honors after recording 48 tackles and seven passes defensed, while helping the Huskies reach the College Football Playoff semifinals.

Following his final season, Prysock participated in the 2026 NFL Scouting Combine, where he recorded a 4.45-second 40-yard dash and a 39-inch vertical jump

Measurements

The following are the official measurements from the NFL Scouting Combine.

• Height: 6-3
• Weight: 196 lbs
• Arms: 33 1/8 inches
• Hands: 9 3/4 inches

NFL Scouting Combine

The following are the official testing results from the NFL Scouting Combine.

• 40-yard dash: 4.45 seconds
• 10-yard split: 1.57 seconds
• Vertical jump: 39 inches
• Broad jump: 10 feet, 4 inches

Hometown

Canyon Country, CA

College Statistics

• 2022: Enrolled January 2022
• 2023: Honorable Mention All-Pac 12; blocked FG (returned for TD by teammate)
• 2024: Enrolled January 2024

Scouting Report

Lance Zierlein's NFL.com scouting report:
Prysock is a tall corner with impressive length but a high center of gravity that limits transitions. He's upright in his pedal and can be late at break points in off coverage. He stays more connected when he can press and displays good acceleration/make-up speed when needed. His traits and field awareness fit well with short zone/shell coverages. Regardless of coverage, Prysock's lack of anticipatory aggression and short-area suddenness fail to generate enough on-ball production, which limits his upside.

Lance Zierlein's Player Comparison:
Decamerion Richardson

NFL.com Draft Bio:

• 2022 (Arizona): Played in 10 games with 3 starts (16 tackles).
• 2023 (Arizona): Honorable Mention All-Pac-12 Conference. Started all 13 games (61 tackles, TFL, INT, 7 PBUs, blocked kick).
• 2024: Started all 13 games (45 tackles, 6 PBUs, FF).
• 2025: Tied for the team lead with 7 PBUs. Started all 13 games (48 tackles, TFL, INT).

Pre-Draft Grade:
Prysock earned a pre-draft grade of 6.17 from NFL.com, which equates to a "good backup with potential to develop into a starter," per the site's 8-point grading scale.

Projection:
NFL.com projected Prysock to be a fourth-round draft pick.

Pro Football Focus (PFF) Grades:
Ephesians Prysock is a cornerback for the Washington Huskies who earned a 77.2 overall PFF defensive grade in the 2025 season, 137th among 897 qualified cornerbacks. His PFF coverage grade of 75.8 ranked 180th among 897 qualified cornerbacks. His run-defense grade of 82.2 ranked 78th at the position.

More Draft Analysis

Dane Brugler of The Athletic's Analysis:
A tall, long-limbed athlete, Prysock can carry receivers vertically or close on throws with linear burst. He uses his length to affect the catch point but tends to be handsy through routes and isn't natural playing the football. He doesn't consistently trust his technique or speed, which is the root of several of his issues, leaving him unbalanced and tardy to react.

Mike Renner of CBS Sports' Analysis:
Prysock is a long, smooth cornerback who didn't give up much this past fall. I wish he had a little more ball production, but he forced plenty of incompletions without needing to get his hands on the ball.