49ers to waive DE Drake Jackson

A knee injury has sidetracked Drake Jackson‘s career, and the former second-round pick will no longer move forward as a 49er. The team is waiving the young defensive end, ESPN’s Adam Schefter reports.

Jackson missed the entire 2024 season with an injury sustained in 2023. While Schefter adds the USC product is expected to be cleared by training camp, the 49ers are moving on via a failed physical designation Friday. One season remains on Jackson’s rookie contract.

Although Jackson had not secured a starting role before his knee injury, the issue stalled his development midway through the 2023 season. Jackson played in 15 games as a rookie but only eight in 2023. Jackson, 24, will undoubtedly generate interest as a second-chance candidate. He would be available to teams on the waiver wire until 3pm CT on Monday.

The 49ers chose Jackson 61st overall in 2022. At the time, he joined Arik Armstead and a revolving door of Nick Bosa complements. Jackson registered three sacks as a rookie and showed a bit more promise in Year 2, tallying three more during his abbreviated season. Jackson still only totaled five tackles for loss in his first 23 games, but any hope at becoming a more prominent part of San Francisco’s D-line rotation ended after the injury kept him off the field for the past 1 1/2 seasons.

Placing Jackson on IR in early November of 2023, the 49ers stashed him on the reserve/PUP list to open last season. They did not activate him, effectively creating a crossroads situation for the former well-regarded prospect. The 49ers will take on barely $350K in dead money, stemming from signing bonus proration, as a result of this decision. Even if Jackson clears waivers (while teams wait for his return to full strength), it would surprise if he did not land elsewhere before the 2025 season.

The 49ers signaled their interest in moving on by using their No. 11 overall pick on a D-end (Mykel Williams). Although the team released Leonard Floyd after one season, Yetur Gross-Matos remains on the roster as a Bosa complementary piece.