
Arizona Cardinals wide receiver Marvin Harrison Jr. has been one of the team's top targets since going into the NFL last season. Heading into Sunday's matchup against the Indianapolis Colts, Harrison had 82 career receptions for 1,191 yards and 10 touchdowns.
The Cardinals selected Harrison with the fourth overall pick in the 2024 NFL Draft. He played his college football with the Ohio State Buckeyes. Harrison caught 20 passes for 306 yards and a pair of scores through the first five games this year.
On Sunday, the Cardinals were without quarterback Kyler Murray, who was ruled out before the game with a mid-foot sprain. During the game, Arizona was dealt some more rough news on offense.
Harrison caught a pass over the middle in the second quarter against the Colts on Sunday, but when he was tackled, his head bounced off the turf, and he was removed from the game.
Later, ESPN's Adam Schefter reported that the Cardinals ruled Harrison out for the game with a concussion.
"Cardinals now have downgraded WR Marvin Harrison Jr. to out due to a concussion," Schefter said."
Cardinals now have downgraded WR Marvin Harrison Jr. to out due to a concussion. https://t.co/SLUI74Qow7
— Adam Schefter (@AdamSchefter) October 12, 2025
Before leaving the game, Harrison had caught two passes from backup quarterback Jacoby Brisset, who started on Sunday in place of Murray, for 32 yards.
This concussion is a worrisome one for Cardinals fans who were ready for another big season from their star wide receiver. There is no current timetable for Harrison's return yet, although he will have to pass the NFL's concussion protocol before he can get back on the field.
The Cardinals led the Colts 17-14 midway through the third quarter on Sunday.
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