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Jaguars vs. 49ers Roundtable: Preview, Predictions And More
Nov 12, 2023; Jacksonville, Florida, USA; Jacksonville Jaguars running back Travis Etienne Jr. (1) runs with the ball against San Francisco 49ers during the second quarter at EverBank Stadium. Mandatory Credit: Morgan Tencza-Imagn Images Morgan Tencza-Imagn Images

Jaguars vs. 49ers Roundtable: Preview, Predictions And More

Originally posted on Jacksonville Jaguars on SI
By John Shipley  |  Last updated Sep 27, 2025 1:00 PM ET

The Jacksonville Jaguars will kick off against one of the NFL's undefeated squads this Sunday, taking a trip to the West Coast to face the San Francisco 49ers.

To give you our full, comprehensive preview of Week 4, our team of writers has come together to give our predictions and weigh in on the game's biggest questions.

1) Who wins the chess match: Shanahan or Campanile?

This article first appeared on Jacksonville Jaguars on SI and was syndicated with permission.

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