NFL Week 1: Tennessee Titans vs. New Orleans Saints betting picks, preview

We've got some inter-conference play on our hands in this one between Tennessee and New Orleans. The Titans are coming off a disappointing 2022 after making the playoffs in three straight seasons. The Saints will see what they with newly-acquired quarterback Derek Carr joining the team from Las Vegas.

Tennessee Titans vs. New Orleans Saints: Betting Odds

Spread: New Orleans -3, Over/under: 41 points, Tennessee +140 | New Orleans -166

Tennessee is running it back with Ryan Tannehill, at least to start. The Titans have drafted quarterbacks in each of the past two drafts. If Tannehill struggles, don't be surprised to see Malik Willis or Will Levis at some point. The signing of DeAndre Hopkins at least indicates that the Titans are trying to have a successful year, but I am not convinced.

New Orleans should have a strong offense, and the defense is at least serviceable. Both teams were elite at hitting the under last year, Tennessee was 12-5 to the under and New Orleans was 11-6. The Titans were one of the better teams ATS at 9-7-1, while the Saints were only 7-10 ATS.

Betting Picks for Tennessee vs. New Orleans

New Orleans ML & Derek Carr 250+ passing yards (+245 DK)

I am optimistic that Derek Carr is going to bring a massive upgrade at the quarterback position to this New Orleans offense. Chris Olave is poised for a second-year breakout at WR after a strong rookie season. Michael Thomas is healthy. The team also has nice complementary pass-catchers in WR Rashid Shaheed and TE Juwan Johnson.