Sep 7, 2025; Seattle, Washington, USA; Seattle Seahawks defensive end DeMarcus Lawrence (0) reacts after a play during the second half against San Francisco 49ers at Lumen Field. Steven Bisig-Imagn Images

Seahawks lose key pass veteran pass-rusher vs. Cardinals

Originally posted on Seattle Seahawks on SI
By Connor Benintendi | Last updated Sep 25, 2025 10:21 PM ET

It's a good thing the Seattle Seahawks emphasized depth at their edge rusher positions this offseason.

After Boye Mafe entered the Seahawks' Week 4 game against the Arizona Cardinals with a questionable designation, they will now be without veteran pass-rusher DeMarcus Lawrence for the rest of the contest, per The Tacoma News Tribune's Gregg Bell.

Lawrence suffered a thigh injury early in the first half, but the potential for him to return remained. He was not in pads on the sidline when Seattle returned to the field after halftime.

#Seahawks announce DE DeMarcus Lawrence won't return tonight because of his thigh injury
— Gregg Bell (@gbellseattle) September 26, 2025

With Lawrence out, the Seahawks will rely on Mafe, who ended up playing, Derick Hall and Uchenna Nwosu. The Seahawks already have produced two sacks on Kyler Murray with five minutes remaining in the third quarter.

Lawrence totaled one tackle before being sidelined, and he has 12 tackles and two tackles for loss so far on the season after signing with the Seahawks this offseason.

The Seahawks lead the Cardinals 17-3 late in the third quarter.

This article first appeared on Seattle Seahawks on SI and was syndicated with permission.

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