Tennessee Titans head coach Brian Callahan walks the sideline against the Indianapolis Colts. Christine Tannous/IndyStar / USA TODAY NETWORK via Imagn Images

Titans On SI Shares Predictions For Week 3

Originally posted on Tennessee Titans on SI
By Jeremy Brener | Last updated Sep 19, 2025 9:00 AM ET

The Tennessee Titans are hoping to grab their first win in their Week 3 matchup against the Indianapolis Colts. Here's a look at what the Tennessee Titans On SI staff predicts for the game:

Jeremy Brener

The Titans get their first taste of division action this season against the Colts, but it comes at a pretty bad time.

The Colts offense is clicking on all cylinders and have yet to punt at all this season. Daniel Jones looks like an MVP candidate, making it a tricky game for the Titans to win.

It will take a lot for the Titans to pull this one out. I think Cam Ward makes some strides and finds the end zone again, but the Colts offense will be too much for the Titans to keep up with.

Prediction: Colts 34, Titans 17

Luke Hubbard

The Colts have shocked a lot of people with their play this year.Daniel Jones looks competent and Jonathan Taylor has led a very efficient run game in Indianapolis.

Defensively they’ve looked pretty good as well, giving up just 36 combined points through the first two weeks of the season.

The keys to this game for the Titans will be protecting Cam Ward and stopping the run - two things they haven’t been very good at this year.If they can give Ward time to throw and slow down Taylor, they’ll have a shot, but that’s a lot easier said than done.

Prediction: Colts 27, Titans 17

Jordon Lawrenz

WhileI don’t think the Colts are legit, they’re still going to be good enough to get past this Titans team. I just haven’t seen enough from Ward and the offense to believe anything is going to change this week.

Pollard vs. JT is going to be extremely fun to watch, so I’m excited for that. I expect Ward to connect with Ridley for his first TD of the year, but once again that’ll probably be the only time this offense crosses the end zone.

Prediction: Colts 20, Titans 16

Lane Mills

Cam Ward called this week’s game a “must win,” and I think the Titans finally get one. I look for the Colts to falter a little in their first road game, while Tennessee, given their second week in a row at home, should be able to settle in. If the Titans’ defense can limit Indy’s productivity, Ward and company should have enough momentum as a scoring unit by now to gain the edge.

Prediction: Titans 26, Colts 23

This article first appeared on Tennessee Titans on SI and was syndicated with permission.

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