
Each week, I’ll be looking to spotlight players and defenses that I think have a tough matchup that could prevent them from producing their usual value. However, this is not intended as blanket advice to play fringe players ahead of established studs—for example, even if I call out a negative matchup for Josh Allen, it doesn’t mean he should be benched for Bryce Young—so always consider your own lineup alternatives.
With that out of the way, let’s look at Week 2:
For the gamers out there, when you go from easy cannon fodder to a tough-as-nails boss fight with no ramp up, it’s known as a difficulty spike. Going from facing the Cleveland Browns at home in Week 1 to the Denver Broncos on the road in Week 2 is the NFL equivalent. Yes, I know the Broncos struggled on Monday night, but it was mostly the running game that gave them fits—Patrick Mahomes completed just 15 passes and almost none of them were downfield. To be fair, Lawrence was excellent in a 2025 trip to Mile High, throwing for 279 yards and three scores without a pick. Despite that, I’d still strongly consider my alternatives before plugging Lawrence into my QB1 slot this week. Others I don’t like:
Easily the biggest upset in Week 1 was the Cardinals beating the Los Angeles Chargers on the road. Love was a big part of that, scoring one of the team’s two TDs. He only logged 13 touches, though, which was six fewer than Tyler Allgeier. While I don’t think Allgeier will get more work over the long haul than Love, I do think the split will be a lot closer than some anticipated given that Love was the third overall pick. No matter who runs the ball this Sunday, it figures to be tough going as the Seattle Seahawks allowed the fewest fantasy points per game to opposing backs last season. That pushes Love into flex territory. Others I don’t like:
If you thought Washington’s late-season ascent was a fluke, or that a reinvigorated Brian Thomas Jr. would be back at WR1, a Week 1 performance where Washington led the team in targets (6), receptions (5), and yards (83) while catching one of Lawrence’s four touchdown passes suggests otherwise. Washington cooked the Broncos last December for 145 yards and a score, but I wouldn’t bank on a repeat. Denver completely locked down the Chiefs tandem of Rashee Rice and Xavier Worthy, and you don’t get far in life betting against Patrick Surtain II. I can get behind Washington as a WR3, but not more than that. Others I don’t like:
No team in the NFL allowed fewer receptions to tight ends in 2025 than the Buffalo Bills, which gave up just 46 catches (2.7 per game) for an NFL-low 504 yards. After watching their own defense wilt in Week 1, you’d have to think the Lions are going to let Jahmyr Gibbs do as much of the heavy lifting as possible on Thursday night in an effort to keep Josh Allen and company off the field. Between that and Buffalo’s recent success defending tight ends, I worry about LaPorta generating TE1 numbers. Others I don’t like:
Los Angeles Rams: With Myles Garrett (knee) landing on IR and Aaron Donald still working his way back into shape, I’m not sure I trust the Rams to produce fantasy points outside of clear plus matchups, which the New York Giants are not based on Week 1.
Cincinnati Bengals: The Bengals got off to a phenomenal start defensively. I’m still maintaining a healthy level of skepticism until they show some consistency. As such, I wouldn’t be too quick to trust them in Houston.
Minnesota Vikings: Minnesota eventually broke through against the Green Bay Packers, but through three quarters they’d generated almost nothing. The Bears, meanwhile, were busy hanging 59 points on the Carolina Panthers. The downside is too high to risk trusting this defense in Week 2.
More must-reads:
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