'SNF' takeaways: Broncos pick off Matthew Stafford on final play to win thriller over Rams

Nix only completed 17 of his 34 passes for 186 yards with two TDs and one interception, but this Broncos team made key play after key play and showed that they are never truly out of a game, even when the odds are stacked against them and nothing is going right offensively.

Game MVP: Talanoa Hufanga, safety, Denver Broncos

It is no secret that Denver's offense was not at its best against the Rams, but it did not have to be, with Hufanga completely taking over the game defensively. He delivered the final blow with the game-sealing pick of Stafford in the end zone as time expired.

That alone would have put him in consideration for the player of the game honors, but he also had a pick-six and a third-down sack in the fourth, putting his team on his back and coming away with multiple game-altering plays all the way down to the finish.

Play of the game: Pass-interference call on Rams CB Josh Wallace

After converting a 2nd-and-20 and advancing the ball all the way to the 11-yard-line, the Broncos appeared to be in prime position to pick up the win. The odds swung even more in their favor when the Rams CB was called for pass interference while covering Broncos WR Pat Bryant on the sideline.

Moments after the penalty, NBC rules analyst Terry McAulay disagreed with the call and did not believe that Wallace should have been flagged for pass interference. Since Wallace appeared to remarkably get both feet down in bounds, the Rams would have taken over up three with just over one minute remaining.

Nonetheless, the Broncos eventually punched it in the end zone a few plays later and found a way to escape with a massive win over the Rams. The pass interference call, though, was a huge turning point that late in the game and one that likely would have produced a much different outcome if it had been called differently.

Quote of the night: "How did they do that?!"

NBC Sports' color commentator Cris Collinsworth likely echoed the thoughts of many fans watching Sunday night's game when Nix somehow found wide receiver Jaylen Waddle in the back of the end zone for this remarkable two-point conversion to make it a one-score game midway through the third quarter.

That followed a five-yard TD pass from Nix to Bryant that finally put the Broncos on the board. It took them two-and-a-half quarters to do so, but the throw and ability from Waddle to get both feet down certainly provided a spark that was nonexistent until then.