Columbus Crew vs. St. Louis SC: Preview & Predicted Lineups

• When is the kick-off? Wednesday, October 21st
• What time is kick-off? 8:00 pm ET
• Where is it played? ScottsMiracle-Gro Field, Columbus

Predicted lineups for the Crew vs. St. Louis

Columbus Crew:

• Goalkeeper: Patrick Schulte
• Defenders: Malte Amundsen, Sean Zawadzki, Steven Moreira, Mohamed Farsi
• Midfielders: Santiago Rodriguez, Taha Habroune, André Gomes, Anass Zaroury
• Forwards: Josef Martínez, Brais Méndez

St. Louis SC:

• Goalkeeper: Roman Bürki
• Defenders: Tomas Totland, Timo Baumgartl, Lukas MacNaughton
• Midfielders: Dante Polvara, Chris Durkin, Daniel Edelman, Conrad Wallem, Alexandru Mățan
• Forwards: Rafael Navarro, Jeong Sang-bin

Where to watch Columbus Crew vs. St. Louis SC

The encounter between these two teams will start at 8:00 pm ET at ScottsMiracle-Gro Field in Columbus.

This match is available to watch live on CBS Sports Network/Paramount+.

Injury Report

Columbus Crew:

• OUT: Wessam Abou Ali (knee)
• OUT: Rudy Camacho (torso)

St. Louis SC:

• OUT: Chris Durkin (concussion protocol)
• OUT: Celio Pompeu (knee)

Score Prediction

Based on recent MLS form, St. Louis City SC enters this match as the clear favorite. The visitors are in excellent shape, holding second place in their conference, while the Crew have struggled and remain near the bottom of the Eastern Conference standings.

Still, Columbus Crew's strong tradition in this competition means they cannot be underestimated. Yet, St. Louis' outstanding form suggests that, if they control possession, they are well positioned to claim their first-ever US Open Cup title.

Will see at the end of the matchup who made history, but let’s hope for a fun game to watch.

Score prediction: Columbus Crew 1-2 St. Louis SC.