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Diamondbacks vs. Dodgers Predictions, Picks & Odds For Opening Day Game 1
Zac Gallen and Yoshinobu Yamamoto (Photo by Imagn Images)

Diamondbacks vs. Dodgers: The Arizona Diamondbacks open their 2026 season against the Los Angeles Dodgers in a high-profile Opening Day clash. 

The Diamondbacks enter this one with some uncertainty despite flashes of upside last season. Injuries and inconsistency kept them from building real momentum, and now they head into a tough road environment looking to steal an early win against one of baseball’s elite teams.

The Dodgers, though, are exactly where you’d expect them: right in the middle of the title conversation. After back-to-back championships, expectations haven’t dipped at all.

Diamondbacks vs. Dodgers Starting Pitchers

Yoshinobu Yamamoto gets the Opening Day nod for Los Angeles, and it’s hard to argue with that decision. The World Series MVP was dominant in the postseason, even tossing back-to-back complete games. He’s already proven he can handle the biggest stage.

Zac Gallen will pitch for Arizona after they ruled out Merrill Kelly. Gallen had a rough spring, posting a 7.59 ERA in limited innings. If he can’t settle in early, this could turn into a long outing quickly.

Diamondbacks vs. Dodgers Betting Odds

Team Spread Total Money Line
Arizona Diamondbacks +1.5 O 9 +200
Los Angeles Dodgers -1.5 U 9 -250

The odds heavily lean toward Los Angeles here. Oddsmakers are backing their pitching edge and elite lineup, while Arizona enters as a clear underdog heading into Opening Day.

Diamondbacks vs. Dodgers Expert Prediction

From a pure talent standpoint, the Dodgers have the edge almost everywhere. With Shohei Ohtani anchoring the lineup, they bring constant pressure at the plate and don’t need many mistakes to break a game open.


Shohei Ohtani (Image Credits: Imagn)

Arizona’s path to an upset is simple but difficult – limit baserunners and capitalize early. Players like Corbin Carroll and Ketel Marte need to generate offense quickly before Yamamoto settles in.

Score Prediction: Dodgers 7, Diamondbacks 3

Note: Odds are subject to change, and outcomes are never guaranteed.

This article first appeared on Total Pro Sports and was syndicated with permission.

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