Jacob Misiorowski, William Contreras power Brewers past Nationals

Jacob Misiorowski took a no-hitter into the sixth inning before leaving with a cramp, William Contreras had four hits and the Milwaukee Brewers beat the host Washington Nationals 6-1 on Friday.

Misiorowski came out of the game with a right hamstring cramp after throwing a pitch to James Wood with one out in the sixth. Aaron Ashby came on and carried the no-hit bid into the seventh before Daylen Lile's one-out bloop double.

Contreras had four hits for the second straight game and drove in three runs. Tyler Black had two doubles for Milwaukee, which has won four of five.

Misiorowski (2-2) was dominant, striking out eight and walking two. He retired the last 12 batters he faced, the final four by strikeout. Misiorowski threw 43 pitches of 100+ mph, the third-most in a game in the pitch-tracking era (2008), according to MLB.com.

After throwing a 98.9 mph swinging strike one to Wood, Misiorowski came off the mound and looked into the dugout. Manager Pat Murphy and the team trainer came out, and Misiorowski left the game.

Three Brewers pitchers combined on a two-hitter. Ashby went 2 2/3 frames and Easton McGee pitched a hitless ninth.

Washington starter Jake Irvin (1-4) gave up four runs (three earned) on six hits over five innings.

The Brewers took a quick 1-0 lead. Garrett Mitchell led off the game with a double, went to third on a groundout and scored on passed ball.

In the third, David Hamilton walked and stole second. Brice Turang walked and Contreras lined a single to center, scoring Hamilton.

With one out in the fifth, Turang and Contreras singled and Jake Bauers walked. Luis Rengifo grounded into a fielder's choice to score Turang, and Black doubled, bringing home Contreras to make it 4-0.

CJ Abrams walked in the eighth, went to third on Lile's double and scored on a groundout by Brady House, pulling Washington within 4-1.

The Brewers loaded the bases on two singles and an error with no outs in the eighth. Andre Granillo struck out Mitchell and got Turang to pop out, but Contreras grounded a single to right, scoring two runs.