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Top MLB DFS Start‘em/Sit‘em For August 21st
Denny Medley-Imagn Images

With another week ending soon, fantasy players could end it with a bang in today’s top MLB DFS lineups and fantasy stacks. Thursday’s nine-game slate will end the week in style and could help players win cash prizes. With another week ending, the MLB season is heating up, and fantasy players could end this week with winning cash prizes in today’s top MLB DFS lineups and stacks.

Thursday’s games will end the week with the San Diego Padres taking on their division rival, the San Francisco Giants. Another game that could end the week with a bang is the Kansas City Royals and the T exas Rangers to end the week for fantasy players today. 

With the week heating up for fantasy players, tonight could be another great night for fantasy players for Thursday’s top MLB DFS lineups and fantasy stacks, and players could win cash prizes.

August 21st Top MLB DFS Lineup Starters 

1B/C Salvador Perez, Texas Rangers at Kansas City Royals ($4,000 – DraftKings/2,900-Fanduel)

To start Thursday afternoon’s top MLB DFS lineups, Salvador Perez, of the Kansas City Royals, should be in your lineups. In the losing effort against the Riyals, Perez went 1-3 with a walk during the close loss at home. 

Perez, while sluggish this season, could have a strong performance against the Rangers today. DFS players could see a multi-hit game from the Royals veteran catcher against the Rangers today. 

2B/3B Brett Baty, New York Mets at Washington Nationals ($4,000 – DraftKings/2,700-Fanduel)

Brett Baty of the New York Mets should be in Thursday afternoon’s top MLB DFS lineups for fantasy players. In the close loss against the Nationals, Baty went 1-3 with a home run and a walk

Baty has been heating up for the Mets and could have another solid game today. Fantasy players could expect a multi-hit game from the Mets’ young utility player against a weak Nationals team. 

3B Caleb Durbin, Milwaukee Brewers at Chicago Cubs ($3,700 – DraftKings/2,800-Fanduel)

The last player to have for your fantasy lineups is Caleb Durbin, of the Milwaukee Brewers, in tonight’s top MLB DFS lineups. In the brutal loss against the Cubs, Durbin went 0-1 with a strikeout. 

Durbin has been a lightning in a bottle for the Brewers and could have another solid game today. DFS players could see a multi-hit game from the Brewers infielder who has come out of nowhere for the team’s offense. 

August 21st Top MLB DFS Benchwarmers 

SS Willy Adames, Texas Rangers at Kansas City Royals ($4,500 – DraftKings/3,000-Fanduel) 

Willy Adames is the first player who should be on your top MLB DFS fantasy benc hes for Thursday night’s games. In a crushing loss against the Padres, Adames went 0-3 with a walk during the blowout loss in San Diego. 

Adames has been struggling in his first year as a Giant and could have another poor game today. Fantasy players could see a multi-strikeout game from the Giants’ star shortstop against a strong Padres team.

OF James Wood, New York Mets at Washington Nationals ($5,100 – DraftKings/3,400-Fanduel)

James Wood of the Washington Nat ionals is another player who should be on your fantasy bench in tonight’s Top MLB DFS lineups. In the winning effort against the Mets, Wood went 1-3 with a walk and a strikeout. 

Wood has been having a rough series against the Mets, and his struggles could continue today. Fantasy players could see a multi-strikeout game from the Nationals’ emerging superstar against the Mets’ pitching staff. 

OF Evan Carter, Texas Rangers at Kansas City Royals ($4,200 – DraftKings/3,000-Fanduel) 

Evan Carter of the Texas Rangers should be the last player on your top MLB DFS bench for Thursday afternoon’s games. In the win against the Royals, Carter went 0-4 with a strikeout. 

Carter has been struggling this season and could have another rough game against the Royals. Fantasy players should expect a multi-strikeout game from Carter and should avoid him for the rest of the season for any top MLB DFS lineup and stack.

Total Apex Media Stack Of The Day

May 5, 2025; Bronx, New York, USA; San Diego Padres outfielder Fernando Tatis Jr. (23) reacts after striking out against the New York Yankees during the third inning at Yankee Stadium. Mandatory Credit: John Jones-Imagn Images

Thursday’s top MLB DFS stack should be the San Diego Padres, Fernando Tatis Jr., Ramon Laureano, and Ryan O’Hearn. The Padres have been heating up this August and could have another great game for fantasy lineups. Today could end the week in style, and the Padres’ lineup could help fantasy players win cash prizes in today’s top MLB DFS fantasy stack. 

The first player that should be in today’s top MLB DFS stack of the day is Tatis Jr, who is having another strong season. During the win against the Giants, Tatis Jr. went 2-4 with a double, an RBI, a strikeout, and a walk. Tatis Jr. has been having a solid season for the Padres, and could have another strong game against a weak Giants pitching staff. Fantasy players could see a multi-hit game from the Padres star outfielder against their division rival. 

Another player that fantasy players should have against the Giants is Laureano, who is having a strong stint with the Padres. In the blowout win against the Giants, Laureano went 2-4 with two strikeouts. Laureano has been having a strong stint with the Padres since being traded to the Padres. DFS players could see a multi-hit game from the Padre s veteran outfielder against the Giants’ weak pitching at home. 

The last player for today’s top MLB DFS stack is O’Hearn, who is having a solid season for the Padres. In the win against the Giants, O’Hearn went 2-3 with a home run, two RBIs, and a walk. O’Hearn has been having a solid stint with the Padres since the trade deadline, and could have another great game. Fantasy players could see O’Hearn have a home run against the Giants today to end the week. Today could be another hot one for fantasy lineups in today’s top MLB DFS lineups and fantasy stacks to win cash prizes.

This article first appeared on Total Apex Fantasy Sports and was syndicated with permission.

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