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49ers vs. Jaguars injury report: Purdy limited; Pearsall returns, but still no Jennings

Originally posted on 49ers Webzone | By David Bonilla | Last updated Sep 25, 2025 7:36 PM ET

The San Francisco 49ers are preparing for their Week 4 contest against the Jacksonville Jaguars on Sunday at Levi's Stadium in Santa Clara, California.

Quarterback Brock Purdy continues to practice and is showing progress from the toe injury that sidelined him for the past two games. He's trending toward starting Sunday against the Jaguars.

Ricky Pearsall returned to practice on Thursday after sitting out Wednesday with knee soreness from Sunday's win over the Arizona Cardinals. The second-year wide receiver downplayed the concern, saying, "It's just a little bit of soreness, and I'm not worried about it. If there was a game today, I'd play."

Pearsall leads the San Francisco 49ers with 281 receiving yards this season, ranking third in the entire NFL.

On the other hand, fellow wide receiver Jauan Jennings remains sidelined. Jennings, who missed all of last week's practices and sat out against Arizona, is still dealing with a shoulder injury from Week 1 and an ankle injury from Week 2.

"It's been the same as last week," head coach Kyle Shanahan said Thursday during a radio interview. "Obviously, it is getting better, but hopefully, he'll have an improvement and be able to get out there to practice tomorrow."

Did not see WRs Jauan Jennings or Jordan Watkins during early open portion Thursday.
Ricky Pearsall and Demarcus Robinson leading receiver drills today. pic.twitter.com/i58tRXtIH7
— Nick Wagoner (@nwagoner) September 25, 2025

Wide receiver Jordan Watkins is also expected to be out for an extended stretch after suffering a calf injury last week, keeping him off the practice field.

Defensive end Yetur Gross-Matos returned to practice after missing Wednesday's session with a knee issue. However, defensive tackle C.J. West remains absent following surgery on a broken thumb. The 49ers are hopeful West can suit up this weekend while wearing a protective cast.

Below are Thursday's practice participation reports for both the 49ers and Jaguars, which were provided by the 49ers Communications staff.

San Francisco 49ers Thursday Practice

Did Not Participate In Practice
WR Jauan Jennings (ankle, shoulder), WR Jordan Watkins (calf), DT C.J. West (thumb)

Limited Participation in Practice
G Connor Colby (groin), CB Renardo Green (neck), DE Yetur Gross-Matos (knee), QB Mac Jones (knee), CB Deommodore Lenoir (illness), WR Ricky Pearsall (knee), QB Brock Purdy (left shoulder, toe)

Full Participation in Practice
DT Kalia Davis (ankle), RB Christian McCaffrey (not injury related - resting player), DE Mykel Williams (wrist), T Trent Williams (not injury related - resting player)

Jacksonville Jaguars Thursday Practice

Limited Participation in Practice
WR Dyami Brown (shoulder), G Ezra Cleveland (ankle), G Patrick Mekari (elbow), G Wyatt Milum (knee), RB Bhayshul Tuten (shoulder)

Full Participation in Practice
WR Brian Thomas (wrist)

This article first appeared on 49ers Webzone and was syndicated with permission.

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