Buffalo Bills quarterback Josh Allen. Tina MacIntyre-Yee/Democrat and Chronicle / USA TODAY NETWORK via Imagn Images

Bills vs. Falcons expert predictions Week 6: Is anyone taking Atlanta over Buffalo?

Originally posted on Buffalo Bills on SI
By Mike Moraitis | Last updated Oct 10, 2025 1:27 PM ET

The Buffalo Bills will look to bounce back following their first loss of the 2025 campaign in a Week 6 matchup against the Atlanta Falcons.

The Bills suffered an upset defeat at the hands of the New England Patriots last week to fall to 4-1. Making that loss worse, Patriots fans are now pumping their chests and believe they're team is catching up to Buffalo's perennial AFC East dominance.

Buffalo's chance at redemption against New England, which comes in Week 15, can't come fast enough.

The Falcons are coming out of their bye with a 2-2 record and have yet to put together even a two-game winning streak this season after alternating wins and losses over their first four. Atlanta did, however, notch a win before the bye.

Dale Zanine-Imagn Images

This will be the 14th meeting between these two franchises. It has been an even history between Buffalo and Atlanta, as the Falcons are sporting a 7-6 record over the Bills all time. Buffalo has won each of the last two contests against the Falcons, though.

Here's a look at who experts are picking to win this contest that sees Buffalo as the road team.

ESPN

Stephania Bell: Bills

Matt Bowen: Bills

Mike Clay: Bills

Jeremy Fowler: Bills

Dan Graziano: Bills

Kalyn Kahler: Bills

Pamela Maldonado: Bills

Eric Moody: Bills

Jason Reid: Falcons

Lindsey Thiry: Bills

Seth Wickersham: Bills

CBS Sports

Pete Prisco: Bills

Cody Benjamin: Bills

Jared Dubin: Bills

Ryan Wilson: Bills

John Breech: Bills

Tyler Sullivan: Bills

Dave Richard: Bills

Jamey Eisenberg: Bills

Vinnie Iyer, The Sporting News: Bills 27, Falcons 20

Iyer: "The Bills won't be caught off guard in prime time again and the Falcons tend to be too up-and-down with their young offensive weapons to keep up with Josh Allen and James Cook on the indoor fast track."