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NFL Week 2 predictions
USA TODAY Sports

NFL Week 2 predictions

It only took one week for the 2017 NFL season to deliver a heavy dose of unpredictability. The Chiefs routed the Patriots, but lost Eric Berry for the year in the process. The Texans fell flat against Jacksonville, but the Jags lost Allen Robinson for the season to an ACL injury. Minnesota looked great, while Adrian Peterson stalked Sean Payton on the sidelines. Arizona lost the battle and the war, falling to Detroit and losing David Johnson for two to three months with a wrist injury. 

Still, some familiar sights remained. Antonio Brown was transcendent, the Jets were very, very bad, and most of the league's best quarterbacks led their teams to victory. To Week 2 we go.

 
1 of 16

Houston at Cincinnati (-6.5)

Houston at Cincinnati (-6.5)
Troy Taormina-USA TODAY Sports

Thursday, 8:25 p.m. ET (NFL Network)

Two of Week 1's most disappointing teams do battle here, and both have major issues at quarterback. Deshaun Watson will start for the Texans, as the Tom Savage Era lasted all of one game--at least for now. Andy Dalton, meanwhile, was putrid against Baltimore, posting a dismal 28.4 passer rating, while throwing four interceptions. Still, it is hard to imagine that Dalton will be that bad again, even against a Texans defense that has the tools to give him problems. What is also hard to imagine is that a shell-shocked Houston team will immediately rally behind a rookie quarterback who couldn't win the starting job in the preseason. The Texans have some defensive studs, but the guess here is that the Bengals and Dalton get back on track.

Pick: Bengals

 
2 of 16

Minnesota at Pittsburgh (-6.5)

Minnesota at Pittsburgh (-6.5)
Ken Blaze-USA TODAY Sports

Sunday, 1 p.m. ET (FOX)

The ease with which Minnesota dispatched New Orleans, coupled with the rusty performance from everyone on the Steelers' offense not named Antonio Brown makes this an intriguing, under-the-radar contest in Week 2. Minnesota's offensive line held up, and Dalvin Cook burst on the scene as a versatile weapon for Sam Bradford. His debut, coupled with the work of Stefon Diggs and Adam Thielen, gives Vikings fans plenty of reason for optimism. 

Meanwhile, the Steelers need to get Le'Veon Bell and Martavis Bryant going, and need a much sharper Ben Roethlisberger. Todd Haley's game plan allowed the Browns' defense to dictate terms for large stretches of the game. It's safe to say that in the friendly confines of Heinz Field, the Steelers will test Minnesota's stout defense with plenty more downfield shots. T.J. Watt's success in disrupting Bradford will also be key if the Steelers are to emerge victorious.

Pick: Steelers

 
3 of 16

Cleveland at Baltimore (-7.5)

Cleveland at Baltimore (-7.5)
Ken Blaze-USA TODAY Sports

Sunday, 1 p.m. ET (CBS)

Cleveland's defense performed much better than expected against the Steelers in Week 1, holding them to 14 offensive points. DeShone Kizer did not look overwhelmed either, thanks to a collegiate-style game plan tailored to his strengths. He showed that, when given time, he can stand in and make some throws, though he walked into sacks much too often. 

Baltimore's dominant performance was as surprising as any story in Week 1. The Ravens went on the road and harassed Andy Dalton into four interceptions, while sacking him five times. Joe Flacco's numbers weren't spectacular, but he didn't have to do much to seal up a win. Baltimore will have to find a replacement for Danny Woodhead for the next month or so, but his absence shouldn't hurt them much here. Kizer will find that playing on the road is a different animal, and Baltimore should be able to pin its ears back defensively and wreak havoc.

Pick: Ravens

 
4 of 16

Buffalo at Carolina (-7.5)

Buffalo at Carolina (-7.5)
Kyle Terada-USA TODAY Sports

Sunday, 1 p.m. ET (CBS)

The Bills got a season-opening win last week, but it doesn't feel unfair to suggest that they might not get many more over the next 15 games. LeSean McCoy was his usual superb self, carrying the team to a win over the Jets, but he'll likely find the going much tougher against a Carolina team that churned out a workmanlike win over San Francisco. For their part, the Panthers would doubtless like to get Kelvin Benjamin going. For all the talk about first-round pick Christian McCaffrey, Benjamin remains a major potential difference-maker in the passing game. He only managed one catch for 25 yards on five targets against San Francisco. Look for those numbers to go up as teams key on McCaffrey, and Cam Newton shakes off the last of any remaining rust.

Pick: Panthers

 
5 of 16

Arizona (-7.5) at Indianapolis

Arizona (-7.5) at Indianapolis
Gregory Shamus-Getty Images

Sunday, 1 p.m. ET (FOX)

Arizona's season took a serious hit with the news that David Johnson would miss 2-3 months after wrist surgery, but the hangover from that news should hold off for one week, at least, as the Cardinals get to play what appears to be a truly hapless Colts team. Indianapolis delivered the most embarrassing performance of Week 1, and even with the built-in excuse of Andrew Luck's injury, it's fair to wonder whether or not Chuck Pagano's time as head coach might be running out. The Colts made Jared Goff look pretty good, so even without Johnson at his disposal, Carson Palmer and Larry Fitzgerald should be able to carve up Indy's defense at their leisure. 

Pick: Cardinals

 
6 of 16

Tennessee (-1.5) at Jacksonville

Tennessee (-1.5) at Jacksonville
Shanna Lockwood-USA TODAY Sports

Sunday, 1 p.m. ET (CBS)

Jacksonville's dominant win over Houston was one of Week 1's major surprises, but their test is much tougher against Tennessee this week, even with the game in Jacksonville. The Titans were beaten by Oakland primarily because Derek Carr finished drives with touchdowns and Marcus Mariota did not. Mariota, however, isn't likely to self-destruct the way Tom Savage did, so the Jags will have to earn everything they get. Leonard Fournette was impressive in his debut, and will need to carry an even heavier load for the offense with Allen Robinson lost for the season. Tennessee will look for much greater chemistry and production between Mariota and Eric Decker. Decker was targeted eight times, but finished with just three catches for 10 yards.

Pick: Titans

 
7 of 16

Philadelphia at Kansas City (-4.5)

Philadelphia at Kansas City (-4.5)
Greg M. Cooper-USA TODAY Sports

Sunday, 1 p.m. ET (FOX)

Considering the stage and opponent, no one had a better first week than Kansas City's Kareem Hunt. The vaunted Patriots' defense had no answers for his speed, and more frighteningly for the rest of the AFC, Hunt's presence seemed to embolden Alex Smith, who took plenty of shots downfield, while looking nothing like the conservative game manager he has frequently been dismissed as. Carson Wentz was also impressive in Week 1, but his task gets much tougher, as the noise in Arrowhead Stadium is a completely different animal than what he faced against Washington. Oh, and there is also the matter of Justin Houston, who looks fully back, dangerous, and capable of transforming Kansas City's defense into a truly formidable unit, even without Eric Berry. 

Pick: Chiefs

 
8 of 16

New England (-6.5) at New Orleans

New England (-6.5) at New Orleans
Brad Rempel-USA TODAY Sports

Sunday, 1 p.m. ET (CBS)

Two teams coming off opening-week losses meet in this one, and while New England fans have plenty of reasons to be very optimistic, the same can't be said for New Orleans' partisans. The Saints looked listless and stale against Minnesota, getting sliced and diced by Sam Bradford, Dalvin Cook, Stefon Diggs and Adam Thielen. To make matters worse, there already appears to be plenty of friction between Adrian Peterson and Sean Payton. New Orleans' new-look defense did nothing to differentiate itself from its porous predecessors, and Tom Brady and the Pats will be out to make a statement. Unless the Saints can find a running game and some sort of defensive consistency, this could be a long, ugly afternoon for Drew Brees and company.

Pick: Patriots

 
9 of 16

Chicago at Tampa Bay (-7)

Chicago at Tampa Bay (-7)
Jasen Vinlove-USA TODAY Sports

Sunday, 1 p.m. ET (FOX)

There are no moral victories, especially in the NFL, and so it goes that Chicago's narrow loss to Atlanta in the season opener is just that--a loss. Mike Glennon did enough to quiet Bears fans that would still rather see rookie Mitch Trubisky under center, and if Glennon is keeping Chicago in games, it would make sense to keep trotting him out there so that Trubisky isn't thrown into the fire before he's ready. Chicago's defense hung in there against Matt Ryan, and while Jameis Winston isn't on Ryan's level, he's clearly a young guy on the rise at the position.

Tampa Bay, because of Hurricane Irma, had an extra week off, and therefore extra time to get ready. There is little doubt that citizens of the Tampa area could use a distraction while they clean up from the storm, and the bet is that a talented, motivated and rested Buccaneers team will give them something to cheer about.

Pick: Buccaneers

 
10 of 16

Miami at Los Angeles Chargers (-4.5)

Miami at Los Angeles Chargers (-4.5)
Bill Streicher-USA TODAY Sports

Sunday, 4:05 p.m. ET (CBS)

What happened to the Chargers Monday night was predictable. Philip Rivers played pretty well, but did much of his damage with his team playing catch-up. When they did pull to within three points, the Chargers couldn't complete the comeback. It all added up to what many felt would happen, which was a close loss to a good Denver team sorting out its quarterback issues. 

There is plenty of intrigue surrounding the Dolphins, mainly because no one knows what to expect from Jay Cutler. Here's a guess: Cutler throws a few touchdowns, makes some dynamic plays, then throws an interception or two that leave you scratching your head. Miami would be wise to lean on Jay Ajayi early and often to try to ease Cutler in as much as possible, and set up some low-risk shots downfield.

Pick: Dolphins

 
11 of 16

New York Jets at Oakland (-14)

New York Jets at Oakland (-14)
Christopher Hanewinckel-USA TODAY Sports

Sunday, 4:05 p.m. ET (CBS)

Last Sunday, we learned that Derek Carr is still a step or two above Marcus Mariota in NFL's young quarterback hierarchy, and that Marshawn Lynch can still play. Lynch looked like he hadn't missed a beat after sitting out a year, and Carr looked like a man ready to make the leap into the ranks of the league's elite signal callers. Meanwhile, if the first week was a harbinger of things to come, the Jets seem destined to engage in a season-long battle with Indianapolis to see who will end up with the first pick in the draft. Fourteen points is an enormous spread for any game, let alone one this early in the year, but there's no reason to think that this game will be particularly competitive. 

Pick: Raiders

 
12 of 16

Dallas (-2.5) at Denver

Dallas (-2.5) at Denver
Tim Heitman-USA TODAY Sports

Sunday, 4:25 p.m. ET (FOX)

The recipe for Dallas was simple against New York. Suffocate the Giants' running game, force Eli Manning to win the day without Odell Beckham Jr. in the lineup, and play the hits on offense--namely Ezekiel Elliott and Dak Prescott. That kind of strategy might be more difficult to pull off on the road, even though Trevor Siemian isn't the kind of name that immediately strikes fear in the heart of opponents. Denver's defense figures to try and pressure Prescott and take away Elliott- which is much easier said than done. The clearest path to victory for the Broncos might be to try and control the game with C.J. Anderson and Jamaal Charles, and put Siemian in favorable situations as often as possible.

Pick: Cowboys

 
13 of 16

Washington at Los Angeles Rams (-2.5)

Washington at Los Angeles Rams (-2.5)
Kirby Lee-USA TODAY Sports

Sunday, 4:25 p.m. ET (FOX)

Things don't look half bad for the Rams after one week. Jared Goff was sharp, the defense accounted for two touchdowns and a safety against an undermanned Colts squad. On top of that, Aaron Donald ended his holdout, and seems poised to both start Sunday, and get a lucrative new contract, one that may well make him the highest-paid non-quarterback in the league. L.A.'s defense will get a huge boost with Donald back, which may spell trouble for Kirk Cousins. Cousins was a monument to inefficiency against Philadelphia, completing barely 50 percent of his passes, and notching his only touchdown thanks to a spectacular individual effort from Chris Thompson. If Washington wants to go on the road and win, they'll have to get more from the running game, as Thompson and Robert Kelley combined for a paltry 34 yards on 13 carries. The temptation is to pick the Rams at home, with Donald back, but the fact that the Colts were the opponent in their dominant win gives pause.

Pick: Redskins

 
14 of 16

San Francisco at Seattle (-13.5)

San Francisco at Seattle (-13.5)
Jeff Hanisch-USA TODAY Sports

Sunday, 4:25 p.m. ET (FOX)

The test for Seattle figures to be much easier than it was in Week 1, with an offensively-challenged San Francisco team paying a visit. The Seahawks only managed nine points against Green Bay, which naturally led to speculation that the on-again, off-again feud between the offense and defense would flare back up. So far, indications are that it has not, and a command performance by Russell Wilson would go a long way towards smoothing out any potential tension. Seattle needs to find a running game to make Wilson's life easier, but that might not be easy against a San Francisco defense that limited Carolina to less than four yards per carry in Week 1. Still, Seattle has a lot more talent, and should win easily.

Pick: Seahawks

 
15 of 16

Green Bay at Atlanta (-2.5)

Green Bay at Atlanta (-2.5)
Dennis Wierzbicki-USA TODAY Sports

Sunday, 8:30 p.m. ET (NBC)

Atlanta survived a mediocre Bears team in Week 1, but will need to be much sharper against Green Bay in prime time. This figures to be a shootout between two of the league's top five quarterbacks, and the game may well be a "first team to 35 points wins" kind of affair. Aaron Rodgers didn't put up much in the way of points against a stout Seattle defense, but one assumes he'll have an easier time moving the ball indoors against the Falcons. Still, in a battle between two great offensive football teams, I'll take the one with more balance, not to mention the best non-quarterback on the field in the person of Julio Jones. 

Pick: Falcons

 
16 of 16

Detroit at New York Giants (-4)

Detroit at New York Giants (-4)
Ken Blaze-USA TODAY Sports

Monday, 8:30 p.m. ET (ESPN)

Are Eli Manning's days as a top-tier starter over? He didn't have Odell Beckham Jr., which certainly contributed to his inability to challenge Dallas downfield, but Manning also didn't have the kind of game where he carried an undermanned offense to a win in a hostile environment. If Beckham returns, the offense should uptick considerably. However, his status is day-to-day, and it is anything but guaranteed that he will come back. Without Beckham, it's hard to imagine the Giants' offense being much improved. 

The Lions have an early breakout performer in wide receiver Kenny Golladay, who notched back-to-back touchdowns to help provide the winning margin against Arizona. Golladay, coupled with Golden Tate and Theo Riddick, gives the Lions a versatile group of receiving threats. They may not be able to run the ball against New York, but then again, they may not need to.

Pick: Lions

Chris Mueller is the co-host of The PM Team with Poni & Mueller on Pittsburgh's 93.7 The Fan, Monday-Friday from 2-6 p.m. ET. Owner of a dog with a Napoleon complex, consumer of beer, cooker of chili, closet Cleveland Browns fan. On Twitter at @ChrisMuellerPGH – please laugh.

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