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Arsenal travel to the American Express Stadium on Saturday, September 19, seeking a fifth successive Premier League victory. 

Mikel Arteta’s defending champions have started the campaign in excellent form, beating Ipswich Town, Sunderland, Chelsea and Aston Villa in their opening four league matches.

The Gunners have scored nine goals across those victories and conceded just two. Bukayo Saka has led their attacking numbers, producing three goals from 2.87 expected goals, according to FotMob’s match data. Martin Ødegaard and Christos Tzolis could support him in an attacking set-up that aims to unsettle Brighton’s defence.

However, Arteta faces a selection problem at the back. William Saliba’s absence leaves Arsenal without one of their established central defenders, while Ben White and Cristhian Mosquera face doubts over their availability.

Brighton have their own injury concerns, including Kaoru Mitoma and Evan Ferguson, which could affect their attacking options. Arsenal must still prepare for a difficult away assignment against a side that can create problems through quick passing and movement.

Who are Arsenal’s injured players likely to miss the Brighton game?

1. William Saliba: Back injury

Saliba remains unavailable for selection because of a back injury. FotMob lists his expected return for mid-October 2026, ruling him out of this weekend’s fixture. Gabriel could therefore partner Ezri Konsa in central defence, with Riccardo Calafiori providing further defensive cover.

2. Ben White: Groin injury

White’s groin problem leaves his involvement uncertain. FotMob lists a late-September return, so Arsenal must assess his condition before Arteta confirms the squad. His absence would reduce the manager’s options at right-back.

3. Cristhian Mosquera: Knock

Mosquera appears on FotMob’s injury list with a knock and a doubtful status. Arsenal will need to assess his fitness before the match, particularly with Saliba unavailable.

Suspension issues

Arsenal have no reported suspensions affecting this fixture. The main concerns remain injury-related, with Arteta needing to manage his defensive options carefully.

Arteta’s defensive choices will attract attention before kick-off, particularly if White cannot recover in time. Arsenal’s midfield must provide protection, while Saka and Ødegaard carry much of the creative responsibility. Brighton’s home support will demand concentration from the visitors throughout the match.

Considering Brighton’s severe ten-player injury crisis and Arsenal’s flawless, high-flying start to the season, the Gunners should secure a narrow victory. Despite Saliba’s absence weakening the visitors’ defence, Bukayo Saka’s lethal form should unlock the hosts’ backline to maintain Mikel Arteta’s perfect winning streak.

How have Brighton started the season?

The Seagulls have won 4 games, drawn one and have one loss to Chelsea in the Premier League. They currently sit 5th in the Premier League with 7 points and beat Man United in the Carabao Cup on Wednesday coming back from 2-0 down at Old Trafford.

Via Essential Football

This article first appeared on Essential Football and was syndicated with permission.

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