The Arizona Cardinals play host to the San Francisco 49ers in Week 11 action, and there are several storylines to follow on both sides. In Arizona, a mountain of injuries provides yet another hurdle for the Cardinals while the 49ers are getting Brock Purdy back as their starting quarterback.
As the Arizona Cardinals navigate a turbulent 2025 season, quarterback Kyler Murray’s long-term future with the franchise hangs in the balance, with ESPN insider Jeremy Fowler predicting a likely departure after 2026.
GLENDALE – The Arizona Cardinals injury report for Sunday’s Week 11 game vs. the San Francisco 49ers is laughably long. The 18-player list early in the week has shrunk to 13 on Friday, but the quality of players listed could sink Arizona’s chances before it even touch the field.
GLENDALE – With Marvin Harrison Jr. set to miss the the first game of his career on Sunday, the Arizona Cardinals will need to rely on third-year wide receiver Michael Wilson to finally take the anticipated leap.
NFL draft stock is fluid from the start of the college football season until it concludes. These 20 players have risen up draft boards in 2025 as a result of their strong start to the season.
With eight weeks left in the regular season, it sure feels more likely than not Kyler Murray will be searching for a new home. After what will be seven years of football with the Arizona Cardinals, reports and rumors alike heavily believe Murray's tenure in the desert is done.
TEMPE -- The Arizona Cardinals could be down some major names in Sunday's Week 11 tilt against the San Francisco 49ers. After head coach Jonathan Gannon previously ruled out Marvin Harrison Jr.
GLENDALE – With Marvin Harrison Jr. sidelined due to appendicitis, the Arizona Cardinals aren’t just reshuffling targets, they are highlighting Michael Wilson as the next man up in their matchup against the San Francisco 49ers.
GLENDALE – It seems like every day a new name for the Arizona Cardinals is added to the injury report, and Thursday was no different. The team released its injury report for Sunday’s Week 11 game vs.
TEMPE — After seven seasons in Arizona and one playoff appearance to show for it, the Arizona Cardinals and quarterback Kyler Murray appear to be heading toward a split this offseason.
With the month of September in the books, both the top college prospects and 2026 NFL draft order are coming into focus. Here's a look at our latest first-round NFL mock draft as of October 13, 2025.
Linebacker Josh Sweat was a non-participant on the latest Arizona Cardinals injury report for their Week 11 matchup against the San Francisco 49ers. Sweat (rest) was one of his six players for the Cardinals who did not practice on Thursday.
Jonathan Gannon's future with the Arizona Cardinals continues to be a talking point in the desert as the organization looks to climb its way out of a 3-6 deficit.
Arizona Cardinals OLB Josh Sweat was not spotted at Thursday's practice, and until today's injury report is released, the reason remains unknown. Sweat was not listed on Wednesday's report ahead of Week 11's clash against the San Francisco 49ers.
Darren Urban reports the Cardinals are designating sixth-round OL Hayden Conner to return from injured reserve. Conner has 21 days to return to practice and get activated to the 53-man roster or he will revert to injured reserve for the rest of the year.
The Cardinals are heading into Week 11 with a shorthanded wide receiver room. Zay Jones and Simi Fehoko are both being placed on injured reserve, while Marvin Harrison Jr. will miss at least one game due to a bout of appendicitis, according to ESPN’s Adam Schefter and Josh Weinfuss.
Arizona Cardinals wide receiver Zay Jones suffered a season-ending left Achilles tear in a 44-22 loss to the Seahawks on Sunday, head coach Jonathan Gannon announced (via Josh Weinfuss of ESPN). Jones, who’s expected to undergo surgery, will land on IR.
Kyler Murray was placed on injured reserve this week due to a lingering foot injury, and there are now questions about whether the star quarterback has played his last snap for the Cardinals.