Jaguars Still Doubted Going into Monday Night Football vs. Chiefs

Jaguars home underdogs for primetime

The Jacksonville Jaguars may be riding a two-game win streak over recent perennial playoff teams, but they're about to take on a whole different beast in Week 5. They've played the Kansas City Chiefs five times since Patrick Mahomes took the helm as the new franchise quarterback. They're 0-5 against the two-time MVP.

The Chiefs haven't had the most promising start to the 2025 NFL season. After losing Rashee Rice to a six-game suspension and Xavier Worthy to a dislocated shoulder in the opener, the offense has struggled to move the ball consistently in its first three outings. That led to a disappointing 1-2 record through three weeks.

That all changed last week upon Worthy's return. With the wide receiver back in the fold, the Chiefs were able to drop 37 points on a reeling Baltimore Ravens defense and could have very well scored another touchdown had they not taken their foot off the gas.

Between their promising offensive breakout in Week 4 and the respect they've earned through the years as a modern dynasty, it's not exactly surprising that the Chiefs are favored over the Jaguars, especially in a primetime slot, even on the road. FanDuel has Jacksonville listed at +150 on the moneyline, tabbed as three-point home underdogs.

This game will answer a lot of questions about the Jaguars. Can the defense maintain its historic pace versus a truly elite attack? Can the offense rise to the occasion? Can EverBank Stadium become a better advantage for this team in this new era? The over/under also represents the uncertainty surrounding the units that will take the field Monday night, set at 46.5 points.

Game odds refresh periodically and are subject to change.

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