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The Cubs and Brewers are each down 1 key starter for NLDS
The Cubs and Brewers are each down 1 key starter for NLDS 3

As the Chicago Cubs and Milwaukee Brewers gear up for their NLDS matchup, both organizations have revealed that they will be without one key starting pitcher for the series. On Chicago’s side, Cade Horton won’t be a factor, and on Milwaukee’s side, Brandon Woodruff will remain sidelined.

Both pitchers were long shots to be available for this series, but that has now been confirmed well ahead of when official rosters are released. For Horton, he is recovering from rib fractures while Woodruff a lat strain.

Who will step up for the Chicago Cubs and Milwaukee Brewers in Cade Horton and Brandon Woodruff’s absences?


Chicago Cubs issue murky update on Cade Horton injury 2 Sep 23, 2025; Chicago, Illinois, USA; Chicago Cubs pitcher Cade Horton (22) throws against the New York Mets during the first inning at Wrigley Field. Mandatory Credit: David Banks-Imagn Images

For Game 1, the Cubs will be handing the ball to Matthew Boyd on three days rest. If Cubs manager Craig Counsell follows the same pattern as the Wild Card series, Shota Imanga would then be in line to throw bulk innings on Monday, on four days rest, and Jameson Taillon Wednesday on five days of rest. This would then lineup Boyd again for a potential game four, on as many days rest, and Imanaga on Saturday the 10th, if necessary, on four days rest.

In Chicago’s case, on paper they can navigate this series starting pitching-wise, should it go the distance of five games. However, they will miss Horton’s absence as he had been lights out from the All-Star break on. Should any of the three starters who got the ball in the Wild Card seires falter in the NLDS, it will take a bulk innings reliever like Colin Rea, Aaron Civale, or Michael Soroka to step up and save an already taxed bullpen.

On Milwaukee’s side, Woodruff was slated to start Game 2, as Freddy Peralta is getting the ball in Game 1. Now, Brewers manager Pat Murphy revealed that either Quinn Priester or Jose Quintana will get the ball in Game 2. Woodruff has plenty of postseason experience and clutch performances on his resume, so the Brewers are going to be relying on either a breakout performer in Priester, or a savvy veteran in Quintana, to fill his shoes.

Rookie phenom Jacob Misiorowski is expected to be a bullpen option for the Brewers this series. He had a rough finish to the year, so if Milwaukee calls his name, there will be a lot of eyes on how he performs.

All of this sets the stage for the starting pitching storyline in the NLDS. The Cubs will lean on a carefully managed rotation, hoping their arms hold up on short rest, while the Brewers must find a way to navigate without one of their most reliable postseason performers in Woodruff. It will be interesting to see who comes out on top in what will surely be an emotionally charged series.

This article first appeared on ChiCitySports and was syndicated with permission.

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