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Tennessee Titans vs. Los Angeles Rams Preview, Prediction & Odds | Week 2, 2025
- Oct 6, 2024; Inglewood, California, USA; Los Angeles Rams quarterback Matthew Stafford (9) throws a pass during the third quarter against the Green Bay Packers at SoFi Stadium. Mandatory Credit: Robert Hanashiro-Imagn Images

It will be a battle of old vs. new Sunday in Nashville when the Los Angeles Rams (1-0) take the field against the Tennessee Titans (0-1). This game presents a fascinating contrast between two quarterbacks at opposite ends of their careers.

The veteran Rams quarterback, Matthew Stafford, has thrown for over 60,000 yards in his storied career.  The Titans’ rookie, Cam Ward, has just 112 yards.  This vast gap in experience will be a central storyline as the two teams clash in this early-season matchup.

Los Angeles Rams (1-0) at Tennessee Titans (0-1)
Game Details: Sunday, Sept 14, 1 pm EST
Location: Nashville, TN
Where to Watch: CBS

Betting Odds

Team Spread Total Money Line
Los Angeles Rams -5.5 (-115) Over 41.5 -255
Tennessee +5.5 (-105) Under 41.5  +210

** Odds Courtesy of FanDuel**

Tale of The Tape

Los Angeles Rams Team Stats Tennessee
14 Points Per Game 12
240 Passing Yards Per Game 62
72 Rushing Yards Per Game 71
9 Opponents Points Per Game Allowed 20
151 Opponents Pass Yards Allowed 166
114 Opponents Rush Yards Allowed 151



Key Details

Los Angeles Rams 

The Rams are coming off a 14-9 victory over the Houston Texans in Week 1. The key difference was their efficiency in the red zone, where they converted on two of their three opportunities. 

Stafford led a balanced attack, completing over 72% of his passes for 245 yards and a touchdown. The ground game was also effective, with Kyren Williams rushing for 66 yards on 18 carries. 

Tennessee Titans

Sep 7, 2025; Denver, Colorado, USA; Tennessee Titans quarterback Cam Ward (1) drops back to pass against the Denver Broncos during the first half at Empower Field at Mile High. Mandatory Credit: Ron Chenoy-Imagn Images

The Titans began their season with a 20-12 road loss to the Denver Broncos. Tennessee held a 12-10 lead midway through the third quarter but couldn’t maintain the advantage.  

Tennessee’s offense managed only 133 total yards against a tough Denver defense. Rookie quarterback Ward faced constant pressure, getting sacked six times. Running back Tony Pollard was a bright spot, contributing 60 yards on the ground and another 29 through the air, but it wasn’t enough to overcome the offensive inconsistencies.

Prediction

The Rams are more experienced at Quarterback and Coaching. This is enough to win and cover the spread.

Final Pick

Los Angeles Rams  -5.5 

This article first appeared on Total Apex Fantasy Sports and was syndicated with permission.

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