
On a day full of surprising NFL results, the Indianapolis Colts tried to be spoilers of their own in a Sunday night clash with the Kansas City Chiefs. Despite their best effort, the Colts could not find an answer for quarterback Patrick Mahomes, who returned to his vintage form and delivered a chaotic 33-30 overtime win on "Sunday Night Football."
Here are some takeaways from a wildly entertaining game.
Although Mahomes was relatively quiet in his return to the field in the season-opening win over the Denver Broncos, he was anything but that against the Colts.
Mahomes finished the night 32-of-47 for 382 yards and three touchdowns passing, plus two rushes for 17 yards. As impressive as he was statistically, it was the deep-ball throws and connection with tight end Travis Kelce that really stood out the most.
Kelce led the team with nine catches for 101 yards and added a TD for good measure. According to Yahoo Sports (h/t Chiefs), Kelce officially broke Marshall Faulk's record for career yards after the catch and reminded everyone that he and Mahomes are just as lethal as ever.
Travis Kelce broke the record for career yards after catch in the first half vs. Indy
— Yahoo Sports (@YahooSports) September 21, 2026
(h/t @Chiefs) pic.twitter.com/RzXwRUctbI
Kelce had already turned back the clock with his longest reception (59 yards) since 2021 in the opener, but Sunday night was Mahomes' turn to join the fun and show that any concerns about his ACL injury should be put to rest.
Colts running back Jonathan Taylor played at an MVP level himself with 132 total yards and two TDs, becoming the first player in franchise history to have four TD runs in the first two games of a season, according to the NBC broadcast.
That said, Mahomes gets the nod due to his vintage performance in the clutch. This was not a straightforward win like many expected it to be for the Chiefs, but Mahomes handled the adversity like he always has and was especially clutch with a career-high 14 completions on 17 play-action attempts (h/t Next Gen Stats).
Patrick Mahomes completed 32 of 47 passes for 382 yards and 3 touchdowns in the Chiefs' Week 2 win, recording a career-high 14 completions on play-action passes.
— Next Gen Stats (@NextGenStats) September 21, 2026
He totaled 137 yards and 2 touchdowns on 17 play-action attempts.#INDvsKC | #ChiefsKingdom pic.twitter.com/DiYyyXrqV3
He connected with wide receiver Tyquan Thornton for multiple deep balls, but this one on a 3rd-and-12 in OT was perhaps his biggest one of the game, with the Colts set to get the ball with a chance to win if that pass is not caught.
Mahomes to Thornton on 3rd and 12!
— NFL (@NFL) September 21, 2026
INDvsKC on NBC/Peacock
Stream on @NFLPlus pic.twitter.com/BBMLqfcZHD
The throws were on point all night as Mahomes showed that he is back with a vengeance and looks every bit like his usual self after Sunday night's performance.
After nearly winning the game in a wild turn of events on the previous Colts possession when WR Laquon Treadwell appeared to fumble the ball, officials ultimately overturned the call and said he was down by contact prior to the fumble.
Jones goes deep to Treadwell!
— NFL (@NFL) September 21, 2026
After review it's ruled he was down by contact.
INDvsKC on NBC/Peacock
Stream on @NFLPlus pic.twitter.com/6GLhdpYWwr
After the Colts settled for the field goal, the Chiefs had one final answer with this third-down conversion from Mahomes to running back Kenneth Walker III, which set the stage for the game-winning 40-yard field goal from Harrison Butker.
Kenneth Walker III rumbles the @Chiefs into FG range!
— NFL (@NFL) September 21, 2026
INDvsKC on NBC/Peacock
Stream on @NFLPlus pic.twitter.com/n46H4CBO2f
Harrison Butker wins it for the @Chiefs! pic.twitter.com/OVT4kr1PlD
— NFL (@NFL) September 21, 2026
NBC Sports' color commentator Cris Collinsworth shared his thoughts after Mahomes connected with Kelce for a 13-yard TD in the first quarter.
"One of the most magical combinations in the history of the league." - @CollinsworthPFF pic.twitter.com/6ZE8hbHWYs
— NFL (@NFL) September 21, 2026
More must-reads:
+
Get the latest news and rumors, customized to your favorite sports and teams. Emailed daily. Always free!