Brian Stafford scored 22 points and Denver defeated Texas Southern 62-46 on Saturday.
Rob Lewis added 13 points and Chris Udofia 10 for the Pioneers (6-1). Udofia also had five blocked shots and five assists.
Omar Strong had nine points to lead Texas Southern (1-6). The Tigers only managed 16 points in the first half, shooting just 30 percent. They only trailed by 10, and fared better from the outside in the second half - shooting 57 percent - but Denver shot 61 percent after halftime and opened up a 24-point lead midway through.
The Pioneers, who entered Saturday leading the nation in free-throw accuracy at 83 percent, went 4 for 5 against Texas Southern.
It was the first meeting between the teams.