The Houston Astros' night began with an error and an embarrassing play, and ended with their 100th loss.
Jay Bruce hit a grand slam and had five RBIs, Mike Leake pitched eight scoreless innings and the Cincinnati Reds cruised to a 10-0 win over Houston on Tuesday night.
Cincinnati is 4 1/2 games ahead of Washington for second NL wild card.
The Astros are the first major league team to lose at least 100 games in three straight seasons since Kansas City from 2004-06.
''I'm always going to concentrate on the things we need to do to improve,'' Houston manager Bo Porter said when asked about losing 100 games.
''I don't concern myself with what it is people are going to say. I concern myself about the men in that clubhouse and how we're going to get better every day.''
The Reds got to work early, with Zack Cozart driving in two runs in a four-run first inning.
Cincinnati was up by five in the fourth before Bruce's towering slam to the Crawford Boxes in left field pushed the lead to...